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Machine translation
1. (WO2010028087) NANOPARTICLE-STEM CELL CONJUGATES FOR POST-INFARCTION TREATMENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/028087    International Application No.:    PCT/US2009/055784
Publication Date: 11.03.2010 International Filing Date: 02.09.2009
IPC:
A61L 27/38 (2006.01), A61L 27/54 (2006.01), A61L 27/28 (2006.01), A61L 27/34 (2006.01), A61F 2/02 (2006.01), A61F 2/82 (2006.01)
Applicants: ABBOTT CARDIOVASCULAR SYSTEMS INC. [US/US]; 3200 Lakeside Drive Santa Clara, CA 95054-2807 (US) (For All Designated States Except US).
HENG, Boon, Chin, Alexis [SG/US]; (US) (For US Only).
BASU, Shubhayu [IN/US]; (US) (For US Only).
COWAN, Catherine, M. [US/US]; (US) (For US Only).
DAVALIAN, Dariush [US/US]; (US) (For US Only).
STANKUS, John [US/US]; (US) (For US Only).
DUONG, Duc, H. [VN/US]; (US) (For US Only)
Inventors: HENG, Boon, Chin, Alexis; (US).
BASU, Shubhayu; (US).
COWAN, Catherine, M.; (US).
DAVALIAN, Dariush; (US).
STANKUS, John; (US).
DUONG, Duc, H.; (US)
Agent: ROSE, Bernard, F.; Squire, Sanders & Dempsey L.L.P. 275 Battery Street, Suite 2600 San Francisco, CA 94111 (US)
Priority Data:
61/093,701 02.09.2008 US
Title (EN) NANOPARTICLE-STEM CELL CONJUGATES FOR POST-INFARCTION TREATMENT
(FR) CONJUGUÉS DE CELLULES SOUCHES ET DE NANOPARTICULES POUR UN TRAITEMENT POST-INFARCTUS
Abstract: front page image
(EN)The present invention relates to constructs comprising living cells, preferably stem cells, which have been coated with one or more layers of polyelectrolytes of alternating charge and to the outermost layer of which is electrostatically conjugated nanoparticles that carry one or more therapeutic agents. The invention further relates to the use of the constructs to treat myocardial infarction.
(FR)La présente invention porte sur des produits de construction comprenant des cellules vivantes, de préférence des cellules souches, qui ont été enrobés d'une ou plusieurs couches de polyélectrolytes de charge alternée, et dont la couche la plus externe comporte des nanoparticules électrostatiquement conjuguées portant un ou plusieurs agents thérapeutiques. L'invention concerne en outre l'utilisation des produits de construction pour traiter un infarctus du myocarde.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)