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1. (WO2010027679) MEDICAL DEVICES HAVING COATINGS FOR THERAPEUTIC AGENT DELIVERY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/027679    International Application No.:    PCT/US2009/054397
Publication Date: 11.03.2010 International Filing Date: 20.08.2009
IPC:
A61L 31/08 (2006.01), A61L 31/14 (2006.01), A61L 31/16 (2006.01)
Applicants: BOSTON SCIENTIFIC SCIMED, INC. [US/US]; One Scimed Place Maple Grove, MN 55311-1566 (US) (For All Designated States Except US).
FLANAGAN, Aiden [IE/IE]; (IE) (For US Only)
Inventors: FLANAGAN, Aiden; (IE)
Agent: BONHAM, David, B.; Mayer & Williams PC 251 North Avenue West 2nd Floor Westfield, NJ 07090 (US)
Priority Data:
61/092,355 27.08.2008 US
Title (EN) MEDICAL DEVICES HAVING COATINGS FOR THERAPEUTIC AGENT DELIVERY
(FR) DISPOSITIFS MÉDICAUX MUNIS DE REVÊTEMENTS POUR L'ADMINISTRATION D'AGENTS THÉRAPEUTIQUES
Abstract: front page image
(EN)According to an aspect of the invention, implantable and insertable medical devices are provided that include (a) a substrate, (b) a porous layer comprising interconnected pores disposed over the substrate, (c) at least one first therapeutic agent disposed within and/or beneath the porous layer, (d) a composite layer disposed over the porous layer that includes (i) at least one therapeutic agent eluting region containing at least one second therapeutic agent and at least one matrix material and (ii) at least one bioerodible region containing at least one bioerodible material that extends from the surface of the composite layer to the porous layer.
(FR)Selon un aspect, l'invention concerne des dispositifs médicaux implantables et insérables qui comprennent (a) un substrat, (b) une couche poreuse comprenant des pores interconnectés placée sur le substrat, (b) au moins un premier agent thérapeutique placé à l'intérieur et/ou en dessous de la couche poreuse, (d) une couche composite placée sur la couche poreuse qui comprend (i) au moins une région éluant un agent thérapeutique contenant au moins un deuxième agent thérapeutique et au moins un matériau matrice et (ii) au moins une région bioérodable contenant au moins un matériau bioérodable qui s'étend de la surface de la couche composite jusqu'à la couche poreuse.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)