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1. (WO2010027508) METHODS FOR DIAGNOSIS OR TREATMENT OF AMYLOIDOSIS BY TARGETING HYPER-SULFATED PROTEOGLYCANS PRESENT IN AMYLOID
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/027508    International Application No.:    PCT/US2009/005040
Publication Date: 11.03.2010 International Filing Date: 08.09.2009
IPC:
A61K 31/795 (2006.01), A61K 47/48 (2006.01)
Applicants: UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION [US/US]; 600 Henley Street, Suite 211 Knoxville, TN 37996-4122 (US) (For All Designated States Except US).
THE RADBOUD UNIVERSITY NIJMEGEN MEDICAL CENTRE [NL/NL]; Geert Grooteplein 10 NL-6500 HB Nijmegen (NL) (For All Designated States Except US).
WALL, Jonathan [GB/US]; (US) (For US Only).
KENNEL, Stephen [US/US]; (US) (For US Only).
VAN KUPPEVELT, Toin [NL/NL]; (NL) (For US Only).
SMITS, Nicole [NL/US]; (US) (For US Only)
Inventors: WALL, Jonathan; (US).
KENNEL, Stephen; (US).
VAN KUPPEVELT, Toin; (NL).
SMITS, Nicole; (US)
Agent: EISENBERG, Howard; (US)
Priority Data:
61/191,320 08.09.2008 US
Title (EN) METHODS FOR DIAGNOSIS OR TREATMENT OF AMYLOIDOSIS BY TARGETING HYPER-SULFATED PROTEOGLYCANS PRESENT IN AMYLOID
(FR) PROCÉDÉS DE DIAGNOSTIC OU DE TRAITEMENT D'UNE AMYLOSE PAR CIBLAGE DE PROTÉOGLYCANES HYPERSULFATÉS PRÉSENTS DANS LA SUBSTANCE AMYLOÏDE
Abstract: front page image
(EN)Amyloid in an individual may be targeted by systemically administering to an individual a ligand that binds to a hyper-sulfated proteoglycan and permitting the ligand to bind to hyper-sulfated proteoglycans associated with amyloid within the body of the individual.
(FR)Selon l’invention, la substance amyloïde chez un individu peut être ciblée par l’administration systématique, à un individu, d'un ligand qui se lie à un protéoglycane hypersulfaté et en permettant au ligand de se lier à des protéoglycanes hypersulfatés associés à la substance amyloïde dans le corps de l'individu.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)