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1. (WO2010027344) IMMUNOMODULATORY EXTRACTS FROM LACTOBACILLUS BACTERIA AND METHODS OF MANUFACTURING AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/027344    International Application No.:    PCT/US2008/010350
Publication Date: 11.03.2010 International Filing Date: 04.09.2008
IPC:
A61K 35/74 (2006.01)
Applicants: OM PHARMA [CH/CH]; Rue Du Bois-du-lan 22 CH-1217 Meyrin 2 (CH) (For All Designated States Except US).
BAUER, Jacques, Alain [US/CH]; (CH) (For US Only).
SALVAGNI, Marco [IT/CH]; (CH) (For US Only).
VIGROUX, Jean-pierre, Leon [FR/FR]; (FR) (For US Only).
CHALVET, Laetitia Leela, Gisele [FR/FR]; (FR) (For US Only).
CHIAVAROLI, Carlo [CH/FR]; (FR) (For US Only)
Inventors: BAUER, Jacques, Alain; (CH).
SALVAGNI, Marco; (CH).
VIGROUX, Jean-pierre, Leon; (FR).
CHALVET, Laetitia Leela, Gisele; (FR).
CHIAVAROLI, Carlo; (FR)
Agent: GARRETT, Arthur, S.; Finnegan, Henderson Farabow Garrett & Dunner, LLP 901 New York Avenue, NW Washington, DC 20001-1143 (US)
Priority Data:
Title (EN) IMMUNOMODULATORY EXTRACTS FROM LACTOBACILLUS BACTERIA AND METHODS OF MANUFACTURING AND USE THEREOF
(FR) EXTRAITS IMMUNOMODULATEURS DE BACTÉRIES LACTOBACILLUS ET PROCÉDÉS DE FABRICATION ET D’UTILISATION DE CEUX-CI
Abstract: front page image
(EN)The present invention includes extracts from Lactobacillus bacteria, which may produce immunomodulatory effects in subjects. Embodiments of the invention may be used, for example, as nutraceuticals or pharmaceuticals for treatment of diseases or as adjuvants in medical treatment, such as those related to an imbalance of the production of anti-inflammatory or proinflammatory cytokines. Conditions for which extracts of the invention may be useful include infections, allergies, autoimmunity disorders, and inflammation, or as adjuvants providing healthful benefits in subjects. The invention also includes, inter alia, methods of making and using such extracts. The invention also relates to particular strains of Lactobacillus bacteria.
(FR)La présente invention concerne des extraits de bactéries Lactobacillus, qui peuvent produire des effets immunomodulateurs chez des sujets. Des modes de réalisation de l’invention peuvent être utilisés, par exemple, en tant qu’agents nutraceutiques ou pharmaceutiques pour le traitement de maladies ou en tant qu’adjuvants dans un traitement médical, tel que ceux associés à un déséquilibre de la production de cytokines anti-inflammatoires ou pro-inflammatoires. Les affections pour lesquelles les extraits de l’invention peuvent être utiles comprennent des infections, des allergies, des troubles auto-immuns, et l’inflammation, ou en tant qu’adjuvants produisant des bénéfices pour la santé chez des sujets. L’invention comprend en outre, entre autres, des procédés de fabrication et d’utilisation de tels extraits. L’invention concerne en outre des souches particulières de bactéries Lactobacillus.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)