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1. (WO2010026104) 4-TETRAHYDROPYRAN-AMINOPYRIDINE DERIVATIVES AND THEIR MEDICAL USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/026104    International Application No.:    PCT/EP2009/061125
Publication Date: 11.03.2010 International Filing Date: 28.08.2009
IPC:
C07D 213/40 (2006.01), A61K 31/444 (2006.01), A61P 25/00 (2006.01)
Applicants: NEUROSEARCH A/S [DK/DK]; Pederstrupvej 93 DK-2750 Ballerup (DK) (For All Designated States Except US).
JESSEN, Carsten [DK/DK]; (DK) (For US Only).
BROWN, William, Dalby [DK/DK]; (DK) (For US Only).
STRØBÆK, Dorte [DK/DK]; (DK) (For US Only)
Inventors: JESSEN, Carsten; (DK).
BROWN, William, Dalby; (DK).
STRØBÆK, Dorte; (DK)
Common
Representative:
NEUROSEARCH A/S; Patent Department Pederstrupvej 93 DK-2750 Ballerup (DK)
Priority Data:
PA 2008 01222 03.09.2008 DK
61/094,151 04.09.2008 US
PA 2009 00435 31.03.2009 DK
61/166,844 06.04.2009 US
Title (EN) 4-TETRAHYDROPYRAN-AMINOPYRIDINE DERIVATIVES AND THEIR MEDICAL USE
(FR) DÉRIVÉS DE 4-TÉTRAHYDROPYRANE-AMINOPYRIDINE ET LEUR UTILISATION MÉDICALE
Abstract: front page image
(EN)The present invention relates to novel 4-tetrahydropyran-aminopyridine derivatives, to their use in therapy, to pharmaceutical compositions comprising the derivatives, to the use of said derivatives in the manufacture of a medicament, and to therapeutic methods comprising the administration of the derivatives. The present derivatives are useful for treating a disorder, disease or a condition of a subject, which disorder, disease or condition is responsive to activation of Kv7 channels.
(FR)La présente invention concerne de nouveaux dérivés de 4-tétrahydropyrane-aminopyridine, leur utilisation en thérapie, des compositions pharmaceutiques comprenant les dérivés, l’utilisation desdits dérivés dans la fabrication d’un médicament, et des procédés thérapeutiques comprenant l’administration des dérivés. Les présents dérivés sont utiles pour traiter un trouble, une maladie ou une affection d’un sujet, lesdits trouble, maladie ou affection répondant à l’activation de canaux Kv7.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)