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1. (WO2010025176) MCP-1 DELIVERY SYSTEM
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/025176    International Application No.:    PCT/US2009/055027
Publication Date: 04.03.2010 International Filing Date: 26.08.2009
A61K 47/42 (2006.01), A61K 47/34 (2006.01)
Applicants: VIRGINIA COMMONWEALTH UNIVERSITY [US/US]; 800 E. Leigh St, Ste. 113 Richmond VA 23219 (US) (For All Designated States Except US).
BOWLIN, Gary, L. [US/US]; (US) (For US Only).
SMITH, Matthew, J. [US/US]; (US) (For US Only).
WHITE, Kimber, L., Jr. [US/US]; (US) (For US Only)
Inventors: BOWLIN, Gary, L.; (US).
SMITH, Matthew, J.; (US).
WHITE, Kimber, L., Jr.; (US)
Agent: ARNOLD, Beth, E.; Foley Hoag LLP Seaport World Trade Center West 155 Seaport Blvd. Boston, MA 02210-2600 (US)
Priority Data:
61/092,544 28.08.2008 US
Abstract: front page image
(EN)The present invention is directed to methods and compositions related to electroprocessed drug delivery devices. An electroprocessed drug delivery device of the present invention can, for example, be made to comprise an electrospun scaffold (e.g., comprising polydioxanone) incorporated with Monocyte Chemotactic Protein- 1 (MCP-I). The electroprocess drug delivery device can be used to influence macrophage infiltration and adherence, and to allow extended chemokine release.
(FR)La présente invention concerne des méthodes et des compositions liées aux dispositifs d’administration de médicaments soumis à un traitement électrique. Un dispositif d’administration de médicaments soumis à un traitement électrique de la présente invention peut, par exemple, comprendre un échafaudage produit par filage par voie électrostatique  (par exemple, comprenant du polydioxanone) contenant une protéine chimiotactique des monocytes 1 (MCP-I). Le dispositif d’administration de médicaments soumis à un traitement électrique peut être utilisé pour influencer l’infiltration et l’adhérence des macrophages et pour permettre une libération prolongée des chimiokines.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)