WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2010023322) PROCESS FOR THE PREPARATION OF (3R,3AS,6AR)-HEXAHYDROFURO [2,3-B] FURAN-3-YL (1S,2R)-3-[[(4-AMINOPHENYL) SULFONYL] (ISOBUTYL) AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/023322    International Application No.:    PCT/EP2009/061253
Publication Date: 04.03.2010 International Filing Date: 01.09.2009
IPC:
C07D 493/04 (2006.01)
Applicants: TIBOTEC PHARMACEUTICALS [IE/IE]; Eastgate Village Eastgate Little Island Co Cork (IE) (For All Designated States Except US).
WIGERINCK, Piet Tom Bert Paul [BE/BE]; (BE) (For US Only).
SURLERAUX, Dominique Louis Nestor Ghislain [BE/BE]; (BE) (For US Only).
VERSCHUEREN, Wim Gaston [BE/BE]; (BE) (For US Only).
DE KOCK, Herman Augustinus [BE/BE]; (BE) (For US Only).
AELTERMAN, Wim Albert Alex [BE/BE]; (BE) (For US Only)
Inventors: WIGERINCK, Piet Tom Bert Paul; (BE).
SURLERAUX, Dominique Louis Nestor Ghislain; (BE).
VERSCHUEREN, Wim Gaston; (BE).
DE KOCK, Herman Augustinus; (BE).
AELTERMAN, Wim Albert Alex; (BE)
Agent: DAELEMANS, Frank; J&J Patent Law Department Turnhoutseweg 30 B-2340 Beerse (BE)
Priority Data:
08163383.6 01.09.2008 EP
Title (EN) PROCESS FOR THE PREPARATION OF (3R,3AS,6AR)-HEXAHYDROFURO [2,3-B] FURAN-3-YL (1S,2R)-3-[[(4-AMINOPHENYL) SULFONYL] (ISOBUTYL) AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
(FR) PROCÉDÉ DE PRÉPARATION DU COMPOSÉ (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHÉNYL) SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
Abstract: front page image
(EN)The present invention relates to a process for the preparation of (3R,3a S,6aR)-hexa-hydrofuro [2,3-b] furan-3-yl (1S,2R)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate as well as novel intermediates for use in said process. (3R,3a S,6aR)-hexahydrofuro [2,3-b] furan-3-yl (1S,2R)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate is particularly useful as an HIV protease inhibitor.
(FR)Cette invention concerne un procédé de préparation du composé (3R,3a S,6aR)-hexa-hydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophényl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate, ainsi que de nouveaux intermédiaires à utiliser dans ce procédé. Le composé (3R,3a S,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophényl)sulfonyl](isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate est particulièrement utile comme inhibiteur de la protéase du VIH.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)