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1. WO2010023181 - THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS

Publication Number WO/2010/023181
Publication Date 04.03.2010
International Application No. PCT/EP2009/060876
International Filing Date 24.08.2009
IPC
C07D 495/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
495Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61K 31/381 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
38having sulfur as a ring hetero atom
381having five-membered rings
A61P 9/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
CPC
A61K 31/519
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
A61P 11/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
06Antiasthmatics
A61P 11/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
08Bronchodilators
A61P 13/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
12of the kidneys
A61P 19/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
06Antigout agents, e.g. antihyperuricemic or uricosuric agents
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
Applicants
  • BOEHRINGER INGELHEIM INTERNATIONAL GMBH [DE]/[DE] (AllExceptUS)
  • AUSTEN, Matthias [DE]/[DE] (UsOnly)
  • BLACK, Phillip [GB]/[GB] (UsOnly)
  • BLACKABY, Wesley [GB]/[GB] (UsOnly)
  • DANILEWICZ, John [GB]/[GB] (UsOnly)
  • LINNEY, Ian [GB]/[GB] (UsOnly)
  • SCHREITER, Kay [DE]/[DE] (UsOnly)
  • SCHNEIDER, Martin [DE]/[DE] (UsOnly)
Inventors
  • AUSTEN, Matthias
  • BLACK, Phillip
  • BLACKABY, Wesley
  • DANILEWICZ, John
  • LINNEY, Ian
  • SCHREITER, Kay
  • SCHNEIDER, Martin
Agents
  • HAMMANN, et al., Heinz
Priority Data
08015049.326.08.2008EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS
(FR) THIÉNOPYRIMIDINES POUR COMPOSITIONS PHARMACEUTIQUES
Abstract
(EN) The present invention relates to novel pharmaceutical compositions comprising thienopyrimidine compounds according to formula (I). Moreover, the present invention relates to the use of the thienopyrimidine compounds of the invention for the production of pharmaceutical compositions for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof wherein X is selected from CH or N.
(FR) La présente invention concerne de nouvelles compositions pharmaceutiques comprenant des composés de thiénopyrimidine selon la formule (I). De plus, la présente invention concerne l'utilisation des composés de thiénopyrimidine de l'invention pour la production de compositions pharmaceutiques pour la prophylaxie et/ou le traitement de maladies qui peuvent être influencées par l'inhibition de l'activité kinase de Mnk1 et/ou Mnk2 (Mnk2a ou Mnk2b) et/ou des variants de ceux-ci où X est choisi parmi CH ou N.
Related patent documents
RU2011110908This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
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