EP2009060876 THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS

1. (WO2010023181) THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS

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Latest bibliographic data on file with the International Bureau

Pub. No.:		WO/2010/023181		International Application No.:		PCT/EP2009/060876
Publication Date:		04.03.2010		International Filing Date:		24.08.2009

IPC:

C07D 495/04 (2006.01), A61K 31/381 (2006.01), A61P 9/00 (2006.01)

Applicants:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH [DE/DE]; Binger Str. 173 55216 Ingelheim Am Rhein (DE) (For All Designated States Except US).
AUSTEN, Matthias [DE/DE]; (DE) (For US Only).
BLACK, Phillip [GB/GB]; (GB) (For US Only).
BLACKABY, Wesley [GB/GB]; (GB) (For US Only).
DANILEWICZ, John [GB/GB]; (GB) (For US Only).
LINNEY, Ian [GB/GB]; (GB) (For US Only).
SCHREITER, Kay [DE/DE]; (DE) (For US Only).
SCHNEIDER, Martin [DE/DE]; (DE) (For US Only)

Inventors:

AUSTEN, Matthias; (DE).
BLACK, Phillip; (GB).
BLACKABY, Wesley; (GB).
DANILEWICZ, John; (GB).
LINNEY, Ian; (GB).
SCHREITER, Kay; (DE).
SCHNEIDER, Martin; (DE)

Agent:

HAMMANN, et al., Heinz; Boehringer Ingelheim GmbH CD Patents Binger Str. 173 55216 Ingelheim Am Rhein (DE)

Priority Data:

08015049.3

26.08.2008

Title

(EN) THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS
(FR) THIÉNOPYRIMIDINES POUR COMPOSITIONS PHARMACEUTIQUES

Abstract:

(EN)The present invention relates to novel pharmaceutical compositions comprising thienopyrimidine compounds according to formula (I). Moreover, the present invention relates to the use of the thienopyrimidine compounds of the invention for the production of pharmaceutical compositions for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2a or Mnk2b) and/or variants thereof wherein X is selected from CH or N.
(FR)La présente invention concerne de nouvelles compositions pharmaceutiques comprenant des composés de thiénopyrimidine selon la formule (I). De plus, la présente invention concerne l'utilisation des composés de thiénopyrimidine de l'invention pour la production de compositions pharmaceutiques pour la prophylaxie et/ou le traitement de maladies qui peuvent être influencées par l'inhibition de l'activité kinase de Mnk1 et/ou Mnk2 (Mnk2a ou Mnk2b) et/ou des variants de ceux-ci où X est choisi parmi CH ou N.

Designated States:

AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).

Publication Language:	English (EN)
Filing Language:	English (EN)

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