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Pub. No.:    WO/2010/022467    International Application No.:    PCT/AU2009/001117
Publication Date: 04.03.2010 International Filing Date: 28.08.2009
Chapter 2 Demand Filed:    08.06.2010    
A61K 31/353 (2006.01), A61P 37/02 (2006.01)
Applicants: NOVOGEN RESEARCH PTY LTD [AU/AU]; 140 Wicks Road North Ryde , New South Wales 2113 (AU) (For All Designated States Except US).
HUSBAND, Alan James [AU/AU]; (AU) (For US Only).
BROWN, David [AU/AU]; (AU) (For US Only).
HERST, Patries [NL/NZ]; (NZ) (For US Only)
Inventors: HUSBAND, Alan James; (AU).
BROWN, David; (AU).
HERST, Patries; (NZ)
Agent: RECCHIA, Gavin Dean; Davies Collison Cave Level 14 255 Elizabeth Street Sydney , New South Wales 2000 (AU)
Priority Data:
2008904483 29.08.2008 AU
Abstract: front page image
(EN)Composition of isoflavonoids and chromanols and use of them as immunomodulators and as inhibitors of T-cell or T-lymphocyte proliferation. Treatment of disorders involving abnormal proliferation or activity of T cells. Formula (I) where A is hydrogen or optionally substituted phenyl and R1 represents hydroxy, alkoxy, halo or an ester and R2 - R8 represent hydogen, hydroxy, alkyl etc.
(FR)L'invention concerne des compositions d'isoflavonoïdes et de chromanols ainsi que leur utilisation en tant qu'immunomodulateurs et en tant qu'inhibiteurs de la prolifération des lymphocytes T. L'invention concerne également le traitement de troubles impliquant une prolifération ou une activité anormale des lymphocytes T. Dans la formule (I), A représente hydrogène ou phényle éventuellement substitué et R1 représente hydroxy, alkoxy, halo ou un ester et R2-R8 représentent hydrogène, hydroxy, alkyle, etc.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)