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1. (WO2010019099) 2-HYDROXY-ETHANESULFONATE SALT
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2010/019099 International Application No.: PCT/SE2009/050926
Publication Date: 18.02.2010 International Filing Date: 11.08.2009
IPC:
A61K 31/439 (2006.01) ,A61P 11/00 (2006.01) ,A61K 31/42 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
439
the ring forming part of a bridged ring system, e.g. quinuclidine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
42
Oxazoles
Applicants:
NADIN, Alan John [GB/GB]; GB (UsOnly)
ASTRAZENECA AB [SE/SE]; S-151 85 Södertälje, SE (AllExceptUS)
PULMAGEN THERAPEUTICS (SYNERGY) LIMITED [GB/GB]; Fulmer hall Windmill Road Fulmer Slough Berkshire SL3 6HD, GB (AllExceptUS)
Inventors:
NADIN, Alan John; GB
Agent:
ASTRAZENECA AB; AstraZeneca Intellectual Property S-151 85 Södertälje, SE
Priority Data:
0814728.212.08.2008GB
0814729.012.08.2008GB
Title (EN) 2-HYDROXY-ETHANESULFONATE SALT
(FR) SEL 2-HYDROXY-ÉTHANESULFONATE
Abstract:
(EN) The invention provides (R) -1- [3- (R) -cyclohexyl-hydroxy-phenyl- methyl) -isoxazol-5-ylmethyl] -3- (3-f luoro-phenoxy) -1-azonia- bicyclo[2.2.2]octane 2-hydroxy ethanesulf onate, pharmaceutical compositions containing the compound and its use as a muscarinic antagonists, for the treatment of chronic obstructive pulmonary disease.
(FR) L'invention concerne le 2-hydroxy-éthanesulfonate de (R)-1-[3-(R)-cyclohexyl-hydroxy-phényl-méthyl)-isoxazol-5-ylméthyl]-3- (3-fluoro-phénoxy)-1-azonia-bicyclo[2.2.2]octane, des compositions pharmaceutiques renfermant le composé et son utilisation en tant qu'antagoniste muscarinique, pour le traitement de la bronchopneumopathie chronique obstructive.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)