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1. WO2010019098 - PHARMACEUTICAL PRODUCT COMPRISING A MUSCARINIC RECEPTOR ANTAGONIST AND A BETA-2-ADRENOCEPTOR AGONIST

Publication Number WO/2010/019098
Publication Date 18.02.2010
International Application No. PCT/SE2009/050925
International Filing Date 11.08.2009
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
439
the ring forming part of a bridged ring system, e.g. quinuclidine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
06
Antiasthmatics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
08
Bronchodilators
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
471
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02
in which the condensed system contains two hetero rings
08
Bridged systems
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
261
Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
02
not condensed with other rings
06
having two or more double bonds between ring members or between ring members and non-ring members
08
with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
271
Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
02
not condensed with other rings
06
1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
A61K 31/439 (2006.01)
A61P 11/06 (2006.01)
A61P 11/08 (2006.01)
C07D 471/08 (2006.01)
C07D 261/08 (2006.01)
C07D 271/06 (2006.01)
CPC
A61K 31/167
A61K 31/428
A61K 31/439
A61K 45/06
Applicants
  • ASTRAZENECA AB [SE/SE]; S-151 85 Södertälje, SE (AllExceptUS)
  • PULMAGEN THERAPEUTICS (SYNERGY) LIMITED [GB/GB]; Fulmer Hall Windmill Road Fulmer Slough Berkshire SL3 6HD, GB (AllExceptUS)
  • AVITABILE, Barbara Guiseppina [IT/GB]; GB (UsOnly)
  • NADIN, Alan John [GB/GB]; GB (UsOnly)
  • RAY, Nicholas Charles [GB/GB]; GB (UsOnly)
Inventors
  • AVITABILE, Barbara Guiseppina; GB
  • NADIN, Alan John; GB
  • RAY, Nicholas Charles; GB
Agents
  • ASTRAZENECA AB; AstraZeneca Intellectual Property S-151 85 Södertälje, SE
Priority Data
0814728.212.08.2008GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PHARMACEUTICAL PRODUCT COMPRISING A MUSCARINIC RECEPTOR ANTAGONIST AND A BETA-2-ADRENOCEPTOR AGONIST
(FR) PRODUIT PHARMACEUTIQUE CONSTITUÉ D'UN ANTAGONISTE DU RÉCEPTEUR MUSCARINIQUE ET D'UN AGONISTE DU RÉCEPTEUR ADRÉNERGIQUE BÊTA‑2
Abstract
(EN)
The invention provides a pharmaceutical product, kit or composition comprising a first active ingredient which is a selected muscarinic receptor antagonist selected, and a second active ingredient which is a β2-adrenoceptor agonist, of use in the treatment of respiratory diseases such as chronic obstructive pulmonary disease and asthma.
(FR)
L'invention concerne un produit pharmaceutique, un kit ou une composition renfermant un premier principe actif qui est un antagoniste choisi du récepteur muscarinique et un second principe actif qui est un agoniste du récepteur adrénergique β2, utile dans le traitement de maladies respiratoires telles que la broncho-pneumopathie chronique obstructive et l'asthme.
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