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1. WO2010011600 - METHOD FOR REMOVAL OR INACTIVATION OF HEPARIN

Publication Number WO/2010/011600
Publication Date 28.01.2010
International Application No. PCT/US2009/051145
International Filing Date 20.07.2009
IPC
A61M 1/38 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
38Removing constituents from donor blood and returning remainder to body
A61K 38/17 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
C08B 37/10 2006.01
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
BPOLYSACCHARIDES; DERIVATIVES THEREOF
37Preparation of polysaccharides not provided for in groups C08B1/-C08B35/110; Derivatives thereof
10Heparin; Derivatives thereof
CPC
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61M 1/3675
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; ; Extra-corporeal blood circuits
3672Means preventing coagulation
3675Deactivation
A61M 1/3679
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; ; Extra-corporeal blood circuits
3679by absorption
A61M 1/3687
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; ; Extra-corporeal blood circuits
3687Chemical treatment
C07K 14/70503
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
70503Immunoglobulin superfamily
Applicants
  • NORTHWESTERN UNIVERSITY [US]/[US] (AllExceptUS)
  • AMEER, Guillermo, A. [US]/[US] (UsOnly)
  • ZHANG, Yangrong [CN]/[US] (UsOnly)
Inventors
  • AMEER, Guillermo, A.
  • ZHANG, Yangrong
Agents
  • MIAO, Emily
Priority Data
61/082,72822.07.2008US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD FOR REMOVAL OR INACTIVATION OF HEPARIN
(FR) PROCÉDÉ D'ÉLIMINATION OU D'INACTIVATION DE L'HÉPARINE
Abstract
(EN)
The present invention relates to the use of immobilized RAGE or portions thereof for removal of heparin and low molecular weight heparin from a fluid sample or from a patient in need of neutralization of anticoagulant activity. The invention provides a method for removal or inactivation of heparin and low molecular weight heparin, as well as a device which utilizes this method.
(FR)
La présente invention concerne l'utilisation de RAGE immobilisé ou de parties de celui-ci pour éliminer l'héparine et l'héparine de faible poids moléculaire d'un échantillon de fluide ou d'un patient chez lequel il est nécessaire de neutraliser une activité anticoagulante. L'invention concerne un procédé d'élimination ou d'inactivation de l'héparine et de l'héparine de faible poids moléculaire, ainsi qu'un dispositif qui utilise ce procédé.
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