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1. WO2010002877 - BYCYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS

Publication Number WO/2010/002877
Publication Date 07.01.2010
International Application No. PCT/US2009/049234
International Filing Date 30.06.2009
IPC
C07H 19/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
A61K 31/7042 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
CPC
A61P 31/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
A61P 31/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
A61P 31/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
A61P 31/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
16for influenza or rhinoviruses
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07H 19/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides ; Anhydro-derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
Applicants
  • BIOTA SCIENTIFIC MANAGEMENT [AU]/[AU] (AllExceptUS)
  • BOEHRINGER INGELHEIM INTERNATIONAL GMBH [DE]/[DE] (AllExceptUS)
  • FRANCOM, Paula [US]/[US] (UsOnly)
  • FREY, Barbara [DE]/[AU] (UsOnly)
  • BOND, Silas [AU]/[AU] (UsOnly)
  • DRAFFAN, Alistair, George [GB]/[AU] (UsOnly)
  • HARDING, Michael [GB]/[AU] (UsOnly)
  • HUFTON, Richard [AU]/[AU] (UsOnly)
  • JAHANGIRI, Saba [AU]/[AU] (UsOnly)
  • LILLY, Michael, John [NZ]/[AU] (UsOnly)
  • TYNDALL, Edward [AU]/[AU] (UsOnly)
  • DUAN, Jianmin [CA]/[CA] (UsOnly)
  • BETHELL, Richard [GB]/[CA] (UsOnly)
  • KUKOLJ, George [CA]/[CA] (UsOnly)
Inventors
  • FRANCOM, Paula
  • FREY, Barbara
  • BOND, Silas
  • DRAFFAN, Alistair, George
  • HARDING, Michael
  • HUFTON, Richard
  • JAHANGIRI, Saba
  • LILLY, Michael, John
  • TYNDALL, Edward
  • DUAN, Jianmin
  • BETHELL, Richard
  • KUKOLJ, George
Agents
  • STIEBEL, Thomas, R.
Priority Data
61/077,97203.07.2008US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BYCYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS
(FR) NUCLÉOSIDES BICYCLIQUES ET NUCLÉOTIDES CONVENANT COMME AGENTS THÉRAPEUTIQUES
Abstract
(EN)
The present disclosure relates to the use and methods of manufacture of bicyclic nucleosides and nucleotides for the treatment and prevention of infectious and proliferative diseases, including microbial infections and cancer.
(FR)
La présente invention concerne l'utilisation et des procédés de fabrication de nucléosides bicycliques et de nucléotides destinés au traitement et à la prévention d'affections infectieuses et proliférantes, y-compris des infections microbiennes et le cancer.
Also published as
EP2012007443
Latest bibliographic data on file with the International Bureau