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1. (WO2010002115) FXA INHIBITORS WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2010/002115    International Application No.:    PCT/KR2009/003008
Publication Date: 07.01.2010 International Filing Date: 05.06.2009
IPC:
C07D 413/12 (2006.01)
Applicants: LEGOCHEM BIOSCIENCE LTD. [KR/KR]; 461-58 Jeonmin-dong, Yuseong-gu Daejeon 305-811 (KR) (For All Designated States Except US).
SONG, Ho Young [KR/KR]; (KR) (For US Only).
CHO, Young Lag [KR/KR]; (KR) (For US Only).
LEE, Dae Yon [KR/KR]; (KR) (For US Only).
PARK, Hee Sock [KR/KR]; (KR) (For US Only).
BAEK, Sung Yoon [KR/KR]; (KR) (For US Only).
CHAE, Sang Eun [KR/KR]; (KR) (For US Only).
JO, Sang Hui [KR/KR]; (KR) (For US Only).
KIM, Yeon Ok [KR/KR]; (KR) (For US Only).
LEE, Hyang Sook [KR/KR]; (KR) (For US Only).
PARK, Ju Hyun [KR/KR]; (KR) (For US Only).
PARK, Tae Kyo [KR/KR]; (KR) (For US Only).
WOO, Sung Ho [KR/KR]; (KR) (For US Only).
KIM, Yong Zu [KR/KR]; (KR) (For US Only)
Inventors: SONG, Ho Young; (KR).
CHO, Young Lag; (KR).
LEE, Dae Yon; (KR).
PARK, Hee Sock; (KR).
BAEK, Sung Yoon; (KR).
CHAE, Sang Eun; (KR).
JO, Sang Hui; (KR).
KIM, Yeon Ok; (KR).
LEE, Hyang Sook; (KR).
PARK, Ju Hyun; (KR).
PARK, Tae Kyo; (KR).
WOO, Sung Ho; (KR).
KIM, Yong Zu; (KR)
Agent: KWON, Oh-Sig; (KR)
Priority Data:
10-2008-0064178 03.07.2008 KR
Title (EN) FXA INHIBITORS WITH CYCLIC AMIDOXIME OR CYCLIC AMIDRAZONE AS P4 SUBUNIT, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS AND DERIVATIVES THEREOF
(FR) INHIBITEURS DE FXA AVEC L’AMIDOXIME CYCLIQUE OU L’AMIDRAZONE CYCLIQUE EN TANT QUE SOUS-UNITÉ P4, PROCÉDÉS POUR LEUR PRÉPARATION ET COMPOSITIONS PHARMACEUTIQUES ET DÉRIVÉS DE CEUX-CI
Abstract: front page image
(EN)The present invention relates to novel oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone group, pharmaceutically acceptable salts thereof, methods for preparing the same and pharmaceutical compositions comprising the same. The oxazolidinone derivatives with cyclic amidoxime or cyclic amidrazone group or the pharmaceutically acceptable salts thereof can be effectively used for the treatment of thromboembolism and tumor as an anticoagulant based on the inhibition of factor Xa.
(FR)La présente invention concerne de nouveaux dérivés d’oxazolidinone avec un groupe amidoxime cyclique ou amidrazone cyclique, des sels pharmaceutiquement acceptables de ceux-ci, des procédés pour préparer ceux-ci et des compositions pharmaceutiques comprenant ceux-ci. Les dérivés d’oxazolidinone avec un groupe amidoxime cyclique ou amidrazone cyclique ou les sels pharmaceutiquement acceptables de ceux-ci peuvent être efficacement utilisés pour le traitement d’une maladie thromboembolique et d’une tumeur en tant qu’anticoagulant basé sur l’inhibition du facteur Xa.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)