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1. (WO2009152183) SYSTEM AND METHOD FOR HYBRIDIZATION SLIDE PROCESSING
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2009/152183 International Application No.: PCT/US2009/046795
Publication Date: 17.12.2009 International Filing Date: 09.06.2009
IPC:
G01N 35/02 (2006.01) ,G01N 33/50 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
35
Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/-G01N33/148; Handling materials therefor
02
using a plurality of sample containers moved by a conveyer system past one or more treatment or analysis stations
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
Applicants:
F. HOFFMAN-LA ROCHE AG [CH/CH]; Grenzacherstrasse 124 CH-4070 Basel, CH (AllExceptUS)
ADEY, Nils [US/US]; US (UsOnly)
MOYER, Tom [US/US]; US (UsOnly)
PARRY, Rob [US/US]; US (UsOnly)
EMERY, Dale [US/US]; US (UsOnly)
Inventors:
ADEY, Nils; US
MOYER, Tom; US
PARRY, Rob; US
EMERY, Dale; US
Agent:
OSBORNE, David, W.; Thorpe North & Western LLP P.O. Box 1219 Sandy, UT 84091-1219, US
Priority Data:
12/207,34309.09.2008US
61/060,07009.06.2008US
61/150,59906.02.2009US
Title (EN) SYSTEM AND METHOD FOR HYBRIDIZATION SLIDE PROCESSING
(FR) SYSTÈME ET PROCÉDÉ DE TRAITEMENT DE LAME PAR HYBRIDATION
Abstract:
(EN) A system 300 for the substantially-automated hybridization of a plurality of microarray slides. The system comprises an enclosure 310 with a wash basin 312 having an open top end, a lower carrier rotor 330 disposed within the wash basin on a support axle 318 for receiving a plurality of microarray slide substrates 362, and an upper clamp rotor 340 disposed above the lower carrier rotor on the support axle for receiving a plurality of disposable chamber assemblies 240. The system is further configured so that lowering the upper clamp rotor to engage with the lower carrier rotor couples the plurality of chamber assemblies to the plurality of slide substrates to form a plurality of sealed reaction chambers 244, and raising the upper clamp rotor to disengage from the lower carrier rotor de-couples the plurality of chamber assemblies from the plurality of slide substrates to unseal the plurality of reaction chambers.
(FR) L'invention porte sur un système 300 pour l'hybridation sensiblement automatisée d'une pluralité de lames de microréseau. Le système comprend une enceinte 310 avec un bassin de lavage 312 ayant une extrémité supérieure ouverte, un rotor de support inférieur 330 disposé à l'intérieur du bassin de lavage sur un axe de support 318 pour recevoir une pluralité de substrats de lame de microréseau 362, et un rotor de pince supérieur 340 disposé au-dessus du rotor de support inférieur sur l'axe de support pour recevoir une pluralité d'ensembles chambres jetables 240. Le système est en outre configuré de telle sorte que l'abaissement du rotor de pince supérieur pour venir en prise avec le rotor de support inférieur assure le couplage de la pluralité d'ensembles de chambres à la pluralité de substrats de lame pour former une pluralité de chambres de réaction 244 scellées de manière étanche, et l'élévation du rotor de pince supérieur pour se désengager du rotor de support inférieur permet le découplage de la pluralité d'ensembles de chambres de la pluralité de substrats de lame pour desceller la pluralité de chambres de réaction.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2291663JP2011524016US20110190153CN102308217CA2727445