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Pub. No.:    WO/2009/143524    International Application No.:    PCT/US2009/045183
Publication Date: 26.11.2009 International Filing Date: 26.05.2009
A61K 39/29 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF MICHIGAN [US/US]; 1214 South University Avenue, 2nd Floor Ann Arbor, MI 48104 (US) (For All Designated States Except US).
BAKER, James, R., Jr. [US/US]; (US) (For US Only).
BIELINSKA, Anna, U. [PL/US]; (US) (For US Only).
MANK, Nicholas, J. [US/US]; (US) (For US Only).
MAKIDON, Paul, E. [US/US]; (US) (For US Only).
KNOWLTON, Jessica, A. [US/US]; (US) (For US Only).
BLANCO, Luz, P. [CL/US]; (US) (For US Only).
CAO, Zhengyi [US/US]; (US) (For US Only).
SCOTT, Alison, J. [US/US]; (US) (For US Only).
NIGAVEKAR, Shraddha, S. [IN/US]; (US) (For US Only)
Inventors: BAKER, James, R., Jr.; (US).
BIELINSKA, Anna, U.; (US).
MANK, Nicholas, J.; (US).
MAKIDON, Paul, E.; (US).
KNOWLTON, Jessica, A.; (US).
BLANCO, Luz, P.; (US).
CAO, Zhengyi; (US).
SCOTT, Alison, J.; (US).
NIGAVEKAR, Shraddha, S.; (US)
Agent: SISK, Tyler, J.; Casimir Jones S.C. 440 Science Drive, Suite 203 Madison, WI 53711 (US)
Priority Data:
61/055,818 23.05.2008 US
Abstract: front page image
(EN)The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides immunogenic compositions and methods of using the same to induce immune responses (e.g., immunity (e.g., protective immunity) against Hepatitis B virus (HBV) and/or against one or a plurality of pathogens (e.g., vaccinia virus, H5N1 influenza virus, Bacillus anthracis, C. botulinum, Y. pestis, Hepatits B, and/or HIV, etc.)) in a subject. Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.
(FR)L’invention concerne des procédés et compositions pour la stimulation de réponses immunitaires. Spécifiquement, la présente invention concerne des compositions immunogènes et des procédés d’utilisation de celles-ci pour induire des réponses immunitaires (par exemple, immunité (par exemple, immunité protectrice) contre le virus de l’hépatite B (VHB) et/ou contre un ou plusieurs d’une pluralité d’agents pathogènes (par exemple, virus de vaccine, virus de la grippe H5N1, Bacillus anthracis, C. botulinum, Y. pestis, hépatite B et/ou VIH, etc.)) chez un sujet. Les compositions et procédés de la présente invention trouvent une utilisation, entre autres choses, dans des applications cliniques (par exemple médecine thérapeutique et préventive (par exemple, vaccination)) et de recherche.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)