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1. (WO2009143478) EFFICIENT WELLBEING ASSESSMENT AND IMPROVED TREATMENT PROTOCOL
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/143478    International Application No.:    PCT/US2009/045062
Publication Date: 26.11.2009 International Filing Date: 22.05.2009
IPC:
C12Q 1/00 (2006.01)
Applicants: WEISENTHAL, Larry, Mark [US/US]; (US) (For All Designated States Except US)
Inventors: WEISENTHAL, Larry, Mark; (US)
Agent: MURASHIGE, Kate H.; (US)
Priority Data:
61/055,413 22.05.2008 US
Title (EN) EFFICIENT WELLBEING ASSESSMENT AND IMPROVED TREATMENT PROTOCOL
(FR) ESTIMATION EFFICACE DU BIEN-ÊTRE ET PROTOCOLE DE TRAITEMENT AMÉLIORÉ
Abstract: front page image
(EN)Methods to appraise general health and to assess the effectiveness of therapeutic agents are disclosed. These methods can be performed on blood samples or other bodily fluids and comprise effecting cell death of endothelial cells, staining the dead cells and observing them microscopically. In addition, the invention is directed to combination treatments for neoplastic diseases or other conditions characterized by unwanted angiogenesis by administering an antiangiogenesis agent while maintaining nontoxic levels of ethanol and/or DMSO in the blood.
(FR)L’invention concerne des procédés pour évaluer la santé générale et pour estimer l’efficacité d’agents thérapeutiques. Ces procédés peuvent être effectués sur des échantillons de sang ou d’autres fluides organiques et consistent à effectuer la mort cellulaire de cellules endothéliales, à  colorer les cellules mortes et à les observer au microscope. De plus, l’invention concerne des traitements combinés pour des maladies néoplasiques ou d’autres affections caractérisées par une angiogenèse indésirable par l’administration d’un agent anti-angiogenèse tout en maintenant des taux non toxiques d’éthanol et/ou de DMSO dans le sang.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)