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1. (WO2009143297) CARBONATE PRODRUGS AND METHODS OF USING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/143297    International Application No.:    PCT/US2009/044746
Publication Date: 26.11.2009 International Filing Date: 20.05.2009
IPC:
A01N 57/00 (2006.01)
Applicants: NEUROGESX, INC. [US/US]; 2215 Bridgepointe Parkway, Suite 200 San Mateo, CA 94404 (US) (For All Designated States Except US).
MUHAMMAD, Naweed [PK/US]; (US) (For US Only).
BLEY, Keith, R. [US/US]; (US) (For US Only)
Inventors: MUHAMMAD, Naweed; (US).
BLEY, Keith, R.; (US)
Agent: FECHTER, Eric, J.; (US)
Priority Data:
61/054,765 20.05.2008 US
Title (EN) CARBONATE PRODRUGS AND METHODS OF USING THE SAME
(FR) PROMÉDICAMENTS CARBONATÉS ET LEURS MÉTHODES D'UTILISATION
Abstract: front page image
(EN)The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.
(FR)L'invention porte sur des promédicaments carbonatés comprenant un fragment d'anhydride phosphorique carbonique lié au groupe hydroxyle ou carboxyle d'un fragment de médicament parent. Lesdits promédicaments peuvent avoir des propriétés physicochimiques améliorées par rapport aux médicaments parents. L'invention porte également sur des méthodes de traitement de maladies ou états répondant au médicament parent et utilisant lesdits promédicaments carbonatés, ainsi que sur des doses unitaires et des trousses.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)