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1. (WO2009143035) METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING CERVICAL INTRAEPITHELIAL NEOPLASIA AND CERVICAL CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/143035    International Application No.:    PCT/US2009/044287
Publication Date: 26.11.2009 International Filing Date: 18.05.2009
IPC:
C12Q 1/68 (2006.01), C12N 15/11 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street, 12th Floor Oakland, CA 94607-5200 (US) (For All Designated States Except US).
SRIVATSAN, Eri, S. [US/US]; (US) (For US Only).
VEENA, Mysore, S. [IN/US]; (US) (For US Only)
Inventors: SRIVATSAN, Eri, S.; (US).
VEENA, Mysore, S.; (US)
Agent: SUNDBY, Suzannah, K.; Smith, Gambrell & Russell, LLP 1130 Connecticut Ave., Nw #1130 Washington, DC 20036 (US)
Priority Data:
61/054,349 19.05.2008 US
Title (EN) METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING CERVICAL INTRAEPITHELIAL NEOPLASIA AND CERVICAL CANCER
(FR) PROCÉDÉS ET COMPOSITIONS DE DIAGNOSTIC ET DE TRAITEMENT D’UNE NÉOPLASIE CERVICALE INTRAÉPITHÉLIALE ET DU CANCER DU COL DE L’UTÉRUS
Abstract: front page image
(EN)Disclosed herein are methods and compositions for diagnosing and treating diseases associated with a loss of cystatin E/M expression including cervical intraepithelial neoplasia and cervical cancer. Genetic mutations and exonic deletions which result in a loss of cystatin E/M expression are also disclosed.
(FR)La présente invention concerne des procédés et des compositions de diagnostic et de traitement de maladies associées à une disparition de l’expression de la cystatine E/M, et comprenant une néoplasie intraépithéliale cervicale et un cancer du col de l’utérus. La présente invention concerne également les mutations génétiques et les délétions exoniques qui résultent en une disparition de l’expression de la cystatine E/M.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)