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Machine translation
1. (WO2009141541) USE OF KIF13A AND AP-1 INHIBITORS FOR INHIBITING MELANOGENESIS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/141541    International Application No.:    PCT/FR2009/050737
Publication Date: 26.11.2009 International Filing Date: 21.04.2009
IPC:
A61K 8/60 (2006.01), A61K 8/73 (2006.01), C12N 15/11 (2006.01), A61K 31/7088 (2006.01), A61Q 19/02 (2006.01), A61P 17/00 (2006.01), A61K 31/7105 (2006.01)
Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE [FR/FR]; 3 rue Michel Ange F-75016 Paris (FR) (For All Designated States Except US).
INSTITUT CURIE [FR/FR]; 26 rue d'Ulm F-75248 Paris cedex 05 (FR) (For All Designated States Except US).
RAPOSO, Graça [PT/FR]; (FR) (For US Only).
DELEVOYE, Cédric [FR/FR]; (FR) (For US Only).
TENZA, Danièle [FR/FR]; (FR) (For US Only).
HURBAIN, Ilse [FR/FR]; (FR) (For US Only)
Inventors: RAPOSO, Graça; (FR).
DELEVOYE, Cédric; (FR).
TENZA, Danièle; (FR).
HURBAIN, Ilse; (FR)
Agent: GALLOIS, Valérie; (FR)
Priority Data:
08 52692 22.04.2008 FR
08 52696 22.04.2008 FR
Title (EN) USE OF KIF13A AND AP-1 INHIBITORS FOR INHIBITING MELANOGENESIS
(FR) UTILISATION D' INHIBITEURS DE KIF13A ET D ' AP-1 POUR INHIBER LA MELANOGENESE
Abstract: front page image
(EN)The present invention relates to novel pharmaceutical or cosmetic compositions comprising at least one inhibitor of a subunit of the AP‑1 adaptor complex, of a kinesin which interacts with AP‑1, in particular Kif13A, or of the interaction between a subunit of the AP‑1 adaptor complex and said kinesin, and also to the use thereof for the manufacture of a medicament for use in the treatment of pigmentary disorders and as a depigmenting agent.
(FR)La présente invention concerne de nouvelles compositions pharmaceutiques ou cosmétiques comprenant au moins un inhibiteur d'une sous-unité du complexe adaptateur AP-1, d'une kinésine interagissant avec AP-1, en particulier Kif13A, ou de l'interaction entre une sous- unité du complexe adaptateur AP-1 et ladite kinésine, ainsi que leur utilisation pour la fabrication d'un médicament destiné au traitement de troubles pigmentaire et comme agent dépigmentant.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)