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1. (WO2009140863) COMPOSITIONS COMPRISING QUINAZOLINE DERIVATIVES, PREPARATION METHODS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/140863    International Application No.:    PCT/CN2009/000557
Publication Date: 26.11.2009 International Filing Date: 21.05.2009
IPC:
A61K 31/517 (2006.01), C07D 239/94 (2006.01), A61P 35/00 (2006.01), A61P 17/06 (2006.01), A61P 19/02 (2006.01), A61P 11/04 (2006.01), A61P 9/10 (2006.01), A61P 27/02 (2006.01)
Applicants: SHANGHAI ALLIST PHARMAEUTICALS, INC. [CN/CN]; 5th Floor, 1118 Halei Road Zhangjiang High-Tech Park Shanghai 201203 (CN) (For All Designated States Except US).
GUO, Jianhui [CN/CN]; (CN) (For US Only).
HE, Haiying [CN/CN]; (CN) (For US Only)
Inventors: GUO, Jianhui; (CN).
HE, Haiying; (CN)
Agent: CHINA PATENT AGENT (H.K.) LTD.; 22/F, Great Eagle Centre, 23 Harbour Road Wanchai, Hong Kong Special Administration Region (CN)
Priority Data:
200810043382.0 21.05.2008 CN
Title (EN) COMPOSITIONS COMPRISING QUINAZOLINE DERIVATIVES, PREPARATION METHODS AND USES THEREOF
(FR) COMPOSITION CONTENANT DES DÉRIVÉS DE LA QUINAZOLINE, SON PROCÉDÉ DE PRÉPARATION ET SES APPLICATIONS.
(ZH) 包含喹唑啉衍生物的组合物及其制备方法和应用
Abstract: front page image
(EN)Pharmaceutical compositions, which comprise pharmaceutically acceptable salts of N-{4-[3-chloro-4-(3-fluoro-benzyloxy)phenylamino]-quinazoline-6-yl}-acrylamide and optional, medically applicable carriers or diluents, are provided. The said compositions also comprise stabilizers which function as dispersing and/or protecting the active components. Pharmaceutical preparations containing the compositions, methods of preparing the compositions and preparations, and their uses in the treatment of disorders characterized by aberrant erbB family PTKs activity in mammals, are also provided.
(FR)On propose un composé pharmaceutique, contenant des sels de N-{4-[3-chloro-4-(3-fluoro-benzyloxy)phenylamino]-quinazoline-6-yl}-acrylamide de qualité pharmaceutique ainsi que des diluants ou liquides porteurs pharmaceutiques en option. Ledit composéscontient aussi des stabilisateurs dont le rôle est de dissiper et/ou de protéger les principes actifs. Sont aussi proposés des préparations contenant le composé, les procédés de préparation desdits composés et desdites préparations, ainsi que leurs applications dans le traitement de troubles catactérisés par une activité anormale des PTK de la famille erbB chez les mammifères.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)