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Machine translation
1. (WO2009140621) COMPOSITIONS AND METHODS RELATING TO HEAT SHOCK TRANSCRIPTION FACTOR ACTIVATING COMPOUNDS AND TARGETS THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/140621    International Application No.:    PCT/US2009/044186
Publication Date: 19.11.2009 International Filing Date: 15.05.2009
IPC:
A61K 31/415 (2006.01), A61K 31/4155 (2006.01), A61K 31/426 (2006.01), A61P 25/28 (2006.01), A61P 25/16 (2006.01), A61P 35/00 (2006.01)
Applicants: DUKE UNIVERSITY [US/US]; 2812 Erwin Road Suite 306 Durham, NC 27705 (US) (For All Designated States Except US).
THIELE, Dennis, J. [US/US]; (US) (For US Only).
NEEF, Daniel, W. [DE/US]; (US) (For US Only)
Inventors: THIELE, Dennis, J.; (US).
NEEF, Daniel, W.; (US)
Agent: GOETZ, Robert, A.; Casimir Jones S.C. Suite 203 440 Science Drive Madison, WI 53711 (US)
Priority Data:
61/053,513 15.05.2008 US
Title (EN) COMPOSITIONS AND METHODS RELATING TO HEAT SHOCK TRANSCRIPTION FACTOR ACTIVATING COMPOUNDS AND TARGETS THEREOF
(FR) COMPOSITIONS ET PROCÉDÉS AYANT TRAIT AUX COMPOSÉS ACTIVANT LE FACTEUR DE TRANSCRIPTION DE CHOC THERMIQUE ET CIBLES CORRESPONDANTES
Abstract: front page image
(EN)The present invention relates to HSF activating compounds, methods for their discovery, and their research and therapeutic uses. In particular, the present invention provides compounds capable of facilitating HSFl activation, and methods of using such compounds as therapeutic agents to treat a number of conditions associated with protein misfolding.
(FR)La présente invention concerne des composés activant le HSF, des procédés pour leur découverte, et leur recherche et leurs utilisations thérapeutiques. En particulier, la présente invention concerne des composés capables de faciliter l’activation du HSFl, et des procédés destinés à utiliser de tels composés en tant qu’agents thérapeutiques afin de traiter plusieurs états pathologiques associés au mauvais repliement des protéines.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)