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1. (WO2009140572) COMBINATORIAL TREATMENT WITH GLUCOSE REGULATED PROTEIN-170 AND MELANOMA DIFFERENTIATION ASSOCIATED GENE-7
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/140572    International Application No.:    PCT/US2009/044092
Publication Date: 19.11.2009 International Filing Date: 15.05.2009
IPC:
C12N 5/00 (2006.01), A61K 31/70 (2006.01)
Applicants: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK [US/US]; 116 Street And Broadway New York, NY 10027 (US) (For All Designated States Except US).
FISHER, Paul, B. [US/US]; (US) (For US Only).
WANG, Xiang-Yang [--/US]; (US) (For US Only)
Inventors: FISHER, Paul, B.; (US).
WANG, Xiang-Yang; (US)
Agent: ZHONG, Ling; (US)
Priority Data:
61/053,548 15.05.2008 US
Title (EN) COMBINATORIAL TREATMENT WITH GLUCOSE REGULATED PROTEIN-170 AND MELANOMA DIFFERENTIATION ASSOCIATED GENE-7
(FR) TRAITEMENT COMBINATOIRE PAR LA PROTÉINE 170 RÉGULÉE PAR LE GLUCOSE ET PAR LE GÈNE 7 ASSOCIÉ À LA DIFFÉRENCIATION DU MÉLANOME
Abstract: front page image
(EN)The present invention relates to methods of treating cancer comprising administering, to a subject in need of such treatment, an effective amount of a combination of a GRP-170 and a MDA-7 molecule. The combined use of these agents allows effective therapy of cancers that may be relatively resistant to either agent alone.
(FR)L'invention concerne des procédés de traitement du cancer qui consistent à administrer, à un sujet qui a besoin d'un tel traitement, une quantité efficace d'une combinaison entre une molécule GRP- 170 et une molécule MDA-7. L'utilisation combinée de ces agents permet d'obtenir une thérapie efficace contre des cancers qui peuvent être relativement résistants à l'un ou l'autres de ces agents seul.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)