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1. (WO2009140026) RENAL FUNCTION ANALYSIS METHOD AND APPARATUS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/140026    International Application No.:    PCT/US2009/040994
Publication Date: 19.11.2009 International Filing Date: 17.04.2009
IPC:
A61K 49/00 (2006.01), A61B 5/20 (2006.01), A61B 5/00 (2006.01)
Applicants: PHARMACOPHOTONICS, INC. [US/US]; 351 West 10th Street Suite 217 Indianapolis, IN 46202 (US) (For All Designated States Except US).
WANG, Exing [US/US]; (US) (For US Only).
MEIER, Daniel [US/US]; (US) (For US Only).
BUNCH, Robert [US/US]; (US) (For US Only).
MOLITORIS, Bruce [US/US]; (US) (For US Only).
SANDOVAL, Ruben [US/US]; (US) (For US Only).
RUBIN, Matthew [US/US]; (US) (For US Only)
Inventors: WANG, Exing; (US).
MEIER, Daniel; (US).
BUNCH, Robert; (US).
MOLITORIS, Bruce; (US).
SANDOVAL, Ruben; (US).
RUBIN, Matthew; (US)
Agent: KLOBUCHAR, Peter; Ungaretti & Harris LLP 70 West Madison Street Suite 3500 Chicago, IL 60602-4224 (US)
Priority Data:
61/046,273 18.04.2008 US
12/425,827 17.04.2009 US
Title (EN) RENAL FUNCTION ANALYSIS METHOD AND APPARATUS
(FR) PROCÉDÉ ET APPAREIL POUR L’ANALYSE DE LA FONCTION RÉNALE
Abstract: front page image
(EN)A method for measuring a glomerular filtration rate in a mammalian kidney comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the blood stream of a mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the health of the subject's kidney. This method measures volume of plasma distribution based on a fluorescence of a marker molecule relative to a fluorescence of a reporter molecule.
(FR)L’invention concerne un procédé de mesure d’un taux de filtration glomérulaire dans un rein mammalien, qui comprend une source de molécules rapporteuses et de molécules marqueuses fluorescentes. Les molécules fluorescentes sont introduites dans le courant sanguin d’un sujet mammalien. Une mesure des intensités des molécules rapporteuses et des molécules marqueuses fluorescentes est réalisée pendant une certaine durée. Un taux est calculé pour déterminer la santé du rein du sujet. Ce procédé mesure la distribution du volume de plasma en fonction d’une fluorescence d’une molécule marqueuse par rapport à une fluorescence d’une molécule rapporteuse.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)