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1. (WO2009139985) METHODS AND MATERIALS FOR GASTROINTESTINAL DELIVERY OF PATHOGEN/TOXIN BINDING AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/139985    International Application No.:    PCT/US2009/039491
Publication Date: 19.11.2009 International Filing Date: 03.04.2009
IPC:
A61K 35/74 (2006.01), C12N 1/21 (2006.01), C12N 15/74 (2006.01)
Applicants: FARALLONE HOLDINGS BV [NL/NL]; Hobbemakade 118-3 NL-1071 XW Amsterdam (NL) (For All Designated States Except US).
SEEGERS, Jos [NL/NL]; (NL) (For US Only).
CARROLL, Stephen, F. [US/US]; (US) (For US Only)
Inventors: SEEGERS, Jos; (NL).
CARROLL, Stephen, F.; (US)
Agent: MCNICHOLAS, Janet M.; K&L Gates LLP P.O. Box 1135 Chicago, IL 60690-1135 (US)
Priority Data:
61/042,541 04.04.2008 US
Title (EN) METHODS AND MATERIALS FOR GASTROINTESTINAL DELIVERY OF PATHOGEN/TOXIN BINDING AGENTS
(FR) PROCÉDÉS ET MATÉRIAUX POUR ADMINISTRATION GASTRO-INTESTINALE D'AGENTS DE LIAISON PATHOGÈNES/TOXINE
Abstract: front page image
(EN)The present disclosure relates generally to recombinant bacteria (e.g., Lactobacillus) that express one or more binding peptides, antibodies and/or antibody binding fragments on their surface that are specific for one or more pathogens and/or toxins, including toxins from pathogens. The recombinant bacteria may be used for binding, removing and/or neutralizing one or more pathogens and/or toxins, including toxins from pathogens in a gastrointestinal tract.
(FR)L'invention concerne de manière générale des bactéries recombinées (par exemple Lactobacillus) qui expriment un ou plusieurs peptides de liaison, anticorps et/ou fragments de liaison d'anticorps sur leur surface qui sont spécifiques pour un ou plusieurs pathogènes et/ou toxines, comprenant des toxines provenant de pathogènes. Les bactéries recombinées peuvent être utilisées pour liaison, élimination et/ou neutralisation d'un ou plusieurs pathogènes et/ou toxines, comprenant des toxines provenant de pathogènes dans un tractus gastro-intestinal.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)