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1. (WO2009139710) QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/139710    International Application No.:    PCT/SE2009/050527
Publication Date: 19.11.2009 International Filing Date: 12.05.2009
IPC:
C07D 453/02 (2006.01), A61K 31/439 (2006.01), A61P 11/00 (2006.01)
Applicants: ASTRAZENECA AB [SE/SE]; S-SE-151 85 Södertälje (SE) (For All Designated States Except US).
ARGENTA DISCOVERY Ltd. [GB/GB]; 8/9 Spire Green Centre, Flex Meadow Harlow Essex CM19 5TR (GB) (For All Designated States Except US).
FORD, Rhonan [GB/GB]; (GB) (For US Only).
METE, Antonio [IT/GB]; (GB) (For US Only).
MILLICHIP, Ian [GB/GB]; (GB) (For US Only)
Inventors: FORD, Rhonan; (GB).
METE, Antonio; (GB).
MILLICHIP, Ian; (GB)
Agent: ASTRAZENECA AB; AstraZeneca Intellectual Property S-SE-15185 Södertälje (SE)
Priority Data:
0808707.4 13.05.2008 GB
Title (EN) QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS
(FR) DÉRIVÉS DE QUINUCLIDINE ET LEUR UTILISATION COMME ANTAGONISTES DES RÉCEPTEURS MUSCARINIQUES
Abstract: front page image
(EN)The invention provides compounds of formula (I) wherein R1, R2, R3, Het1, n, Y and X are as defined in the specification, a process for their preparation, pharmaceutical compositions containing them, a process for preparing pharmaceutical compositions, their use in therapy and intermediates of use in their preparation
(FR)L'invention porte sur des composés représentés par la formule (I) dans laquelle R1, R2, R3, Het1, n, Y et X sont tels que définis dans la description, sur un procédé pour leur fabrication, sur des compositions pharmaceutiques les contenant, sur un procédé pour la fabrication des compositions pharmaceutiques, sur leur utilisation en thérapie et sur des intermédiaires utiles dans leur fabrication.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)