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1. (WO2009139459) METHOD FOR PREVENTION AND TREATMENT OF METABOLIC SYNDROME THROUGH THE INHIBITION OF PSGL-1
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/139459    International Application No.:    PCT/JP2009/059045
Publication Date: 19.11.2009 International Filing Date: 15.05.2009
Chapter 2 Demand Filed:    28.12.2009    
IPC:
A61K 45/00 (2006.01), A61K 39/395 (2006.01), A61K 48/00 (2006.01), A61P 3/00 (2006.01), A61P 3/04 (2006.01), A61P 3/06 (2006.01), A61P 3/10 (2006.01), A61P 43/00 (2006.01)
Applicants: National University Corporation Okayama University [JP/JP]; 1-1, Tsushima-Naka 1-chome, Kita-ku, Okayama-shi, Okayama 7008530 (JP) (For All Designated States Except US).
SHIKATA, Kenichi [JP/JP]; (JP) (For US Only).
MAKINO, Hirofumi [JP/JP]; (JP) (For US Only).
SATO, Chikage [JP/JP]; (JP) (For US Only)
Inventors: SHIKATA, Kenichi; (JP).
MAKINO, Hirofumi; (JP).
SATO, Chikage; (JP)
Agent: TAKASHIMA, Hajime; Meiji Yasuda Seimei Osaka Midosuji Bldg., 1-1, Fushimimachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410044 (JP)
Priority Data:
2008-128086 15.05.2008 JP
Title (EN) METHOD FOR PREVENTION AND TREATMENT OF METABOLIC SYNDROME THROUGH THE INHIBITION OF PSGL-1
(FR) PROCÉDÉ POUR LA PRÉVENTION ET LE TRAITEMENT DU SYNDROME MÉTABOLIQUE PAR L'INHIBITION DE PSGL-1
(JA) PSGL-1阻害によるメタボリックシンドロームの予防及び治療法
Abstract: front page image
(EN)Disclosed is a prophylactic and/or therapeutic agent which can exhibit an effect by itself on the prevention and/or treatment of a basic condition of a lifestyle-related disease such as metabolic syndrome and type-2 diabetes.  Also disclosed is a method for the screening of the prophylactic and/or therapeutic agent. Specifically disclosed is a prophylactic and/or therapeutic agent for metabolic diseases, which comprises an inhibitor of PSGL-1 as an active ingredient.
(FR)L'invention porte sur un agent prophylactique et/ou thérapeutique qui peut présenter un effet par lui-même sur la prévention et/ou le traitement d'un état de base d'une maladie liée au mode de vie, telle que le syndrome métabolique et le diabète de type 2. L'invention porte également sur un procédé pour le criblage de l'agent prophylactique et/ou thérapeutique. De façon spécifique, l'invention porte sur un agent prophylactique et/ou thérapeutique pour les maladies métaboliques, qui comprend un inhibiteur de PSGL-1 comme principe actif.
(JA) 本発明は、メタボリックシンドロームや2型糖尿病などの生活習慣病における根本的病態の予防及び/又は治療に対して単独で効果をもたらし得る予防及び/又は治療剤やそのスクリーニング方法を提供することをその目的とする。 上記課題は、PSGL-1に対する阻害物質を有効成分として含有する、代謝性疾患の予防及び/又は治療剤によって解決される。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)