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1. (WO2009138778) CYCLOPROPYL BENZAMIDE DERIVATIVES AS INTERMEDIATES FOR CYTOKINE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/138778    International Application No.:    PCT/GB2009/050493
Publication Date: 19.11.2009 International Filing Date: 11.05.2009
IPC:
C07C 237/40 (2006.01), C07C 231/02 (2006.01)
Applicants: ASTRAZENECA AB [SE/SE]; S-151 85 Södertälje (SE) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
ASTRAZENECA UK LIMITED [GB/GB]; 15 Stanhope Gate London Greater London W1K 1LN (GB) (MG only).
BEIJER, Felix [NL/NL]; (NL) (For US Only).
FENNER, Simon [GB/GB]; (GB) (For US Only).
VAN EIJK, Peter [NL/NL]; (NL) (For US Only).
WELHAM, Matthew, James [GB/GB]; (GB) (For US Only).
WYATT, Vanessa [GB/GB]; (GB) (For US Only)
Inventors: BEIJER, Felix; (NL).
FENNER, Simon; (GB).
VAN EIJK, Peter; (NL).
WELHAM, Matthew, James; (GB).
WYATT, Vanessa; (GB)
Agent: ASTRAZENECA INTELLECTUAL PROPERTY; AstraZeneca AB S-151 85 Södertälje (SE)
Priority Data:
61/052,363 12.05.2008 US
Title (EN) CYCLOPROPYL BENZAMIDE DERIVATIVES AS INTERMEDIATES FOR CYTOKINE INHIBITORS
(FR) DÉRIVÉS DE CYCLOPROPYL BENZAMIDE UTILISÉS EN TANT QU'INTERMÉDIAIRES POUR DES INHIBITEURS DE CYTOKINES
Abstract: front page image
(EN)A process for preparing a compound of formula (I) or a pharmaceutically acceptable salt thereof; wherein Qa is as defined in the specification, the compounds being useful in the preparation of therapeutic agents, in particular cytokine inhibitors. Novel compounds of formula (I) are also provided.
(FR)La présente invention concerne un procédé de préparation d'un composé de formule (I) ou d'un sel pharmaceutiquement acceptable de ce dernier. Dans la formule (I), Qa est tel que défini dans la description. Les composés sont utiles dans la préparation d 'agents thérapeutiques, notamment des inhibiteurs de cytokines. De nouveaux composés de formule (I) sont également présentés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)