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1. (WO2009137921) PROGNOSTIC AND PREDICTIVE GENE SIGNATURE FOR NON-SMALL CELL LUNG CANCER AND ADJUVANT CHEMOTHERAPY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/137921    International Application No.:    PCT/CA2009/000650
Publication Date: 19.11.2009 International Filing Date: 14.05.2009
IPC:
C40B 40/06 (2006.01), C12Q 1/68 (2006.01), C40B 30/02 (2006.01), C40B 30/04 (2006.01), G01N 33/574 (2006.01), G01N 33/68 (2006.01), G06F 19/00 (2006.01)
Applicants: UNIVERSITY HEALTH NETWORK [CA/CA]; 190 Elizabeth Street R. Fraser Elliott Building Room 1S-417 Toronto , Ontario M5G 2C4 (CA) (For All Designated States Except US).
TSAO, Ming-Sound [CA/CA]; (CA) (For US Only).
SHEPHERD, Frances, A. [CA/CA]; (CA) (For US Only).
JURISICA, Igor [CA/CA]; (CA) (For US Only).
DER, Sandy, D. [CA/CA]; (CA) (For US Only).
ZHU, Chang-Qi [CA/CA]; (CA) (For US Only).
STRUMPF, Dan [CA/CA]; (CA) (For US Only).
SEYMOUR, Lesley [CA/CA]; (CA) (For US Only).
DING, Keyue [CA/CA]; (CA) (For US Only)
Inventors: TSAO, Ming-Sound; (CA).
SHEPHERD, Frances, A.; (CA).
JURISICA, Igor; (CA).
DER, Sandy, D.; (CA).
ZHU, Chang-Qi; (CA).
STRUMPF, Dan; (CA).
SEYMOUR, Lesley; (CA).
DING, Keyue; (CA)
Agent: BERESKIN & PARR LLP/S.E.N.C.R.L., s.r.l.; 40 King Street West 40th Floor Toronto , Ontario M5H 3Y2 (CA)
Priority Data:
61/071,728 14.05.2008 US
Title (EN) PROGNOSTIC AND PREDICTIVE GENE SIGNATURE FOR NON-SMALL CELL LUNG CANCER AND ADJUVANT CHEMOTHERAPY
(FR) SIGNATURE GÉNIQUE PRÉDICTIVE ET PRONOSTIQUE POUR LE CANCER DU POUMON NON À PETITES CELLULES ET CHIMIOTHÉRAPIE ADJUVANTE
Abstract: front page image
(EN)The application provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups and for determining the benefit of adjuvant chemotherapy by way of a multigene signature. The application also includes kits and computer products for use in the methods of the application.
(FR)L’invention concerne des procédés permettant d’établir un pronostic et de réaliser une classification des patients atteints d’un cancer du poumon, dans des groupes à faible pronostic de survie ou dans des groupes à bon pronostic de survie, et permettant de déterminer le bénéfice d’une chimiothérapie adjuvante au moyen d’une signature multigénique. L’invention concerne également des kits et des produits informatiques utilisés dans le cadre des procédés de la demande de brevet.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)