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1. (WO2009137899) SULFATED GALACTANS WITH ANTITHROMBOTIC ACTIVITY, PHARMACEUTICAL COMPOSITION, METHOD FOR TREATING OR PROPHYLAXIS OF ARTERIAL OR VENOUS THROMBOSIS, METHOD OF EXTRACTION AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/137899    International Application No.:    PCT/BR2009/000125
Publication Date: 19.11.2009 International Filing Date: 12.05.2009
IPC:
C07H 11/00 (2006.01), A61K 31/737 (2006.01)
Applicants: S.A. DELTA DO PRATA [BR/BR]; R. Visconde de Pirajá 430, Grupo 504 22410-002- Ipanema - Rio de Janeiro - RJ (BR)
Inventors: MOURÃO, Paulo Antonio de Souza; (BR).
MELO, Fábio Rabelo; (BR)
Agent: GARCIA, Mario Augusto Soerensen; Soerensen Garcia Advogados Associados Av. Rio Branco 110 - 11° Andar 20040-001 Centro - Rio de Janeiro - RJ (BR)
Priority Data:
PI0801477-9 13.05.2008 BR
C10801477-9 08.05.2009 BR
Title (EN) SULFATED GALACTANS WITH ANTITHROMBOTIC ACTIVITY, PHARMACEUTICAL COMPOSITION, METHOD FOR TREATING OR PROPHYLAXIS OF ARTERIAL OR VENOUS THROMBOSIS, METHOD OF EXTRACTION AND USE THEREOF
(FR) GALACTANES SULFATÉS À ACTIVITÉ ANTITHROMBOTIQUE, COMPOSITION PHARMACEUTIQUE, PROCÉDÉ DE TRAITEMENT OU DE PROPHYLAXIE DES THROMBOSES ARTÉRIELLES OU VEINEUSES, PROCÉDÉ D'EXTRACTION ET D'UTILISATION DE CES GALACTANES
Abstract: front page image
(EN)The present invention relates to low molecular weight sulfated galactans, obtained from algae, particularly genus Botryocladia, preferably species Botryocladia occidentallis, which have no effect on the factor XII activation of the clotting cascade, having antithrombotic heparinoid activity. The present invention also refers to a pharmaceutical composition comprising said sulfated galactans and the use thejreof, as heparin substitute, in the treatment or prophylaxis of arterial or venous thrombosis in humans and animals. Furthermore, the present invention provides a method of extraction of the said sulfated galactans.
(FR)L'invention concerne des galactanes sulfatés de faible poids moléculaire, obtenus à partir d'algues, notamment du genre Botryocladia, de préférence celles de l'espèce Botryocladia occidentallis, qui n'ont aucun effet sur l'activation du facteur XII de coagulation en cascade, possédant une activité héparinoïde antithrombotique. Cette invention concerne également une composition pharmaceutique contenant ces galactanes sulfatés et utilisant ces derniers en tant que substitut de l'héparine, dans le traitement ou la prophylaxie des thromboses artérielles ou veineuses chez l'homme ou chez l'animal. Elle concerne, en outre, un procédé d'extraction de ces galactanes sulfatés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)