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1. WO2009137510 - METHOD FOR PROTECTING HUMANS AGAINST SUPERFICIAL VASODILATOR FLUSH SYNDROME

Publication Number WO/2009/137510
Publication Date 12.11.2009
International Application No. PCT/US2009/042888
International Filing Date 05.05.2009
IPC
A61K 31/35 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
A61K 31/44 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
A61K 36/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
CPC
A61K 31/352
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/445
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
445Non condensed piperidines, e.g. piperocaine
A61K 31/4545
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non condensed pyridines; Hydrogenated derivatives thereof
445Non condensed piperidines, e.g. piperocaine
4523containing further heterocyclic ring systems
4545containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
A61K 31/517
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
517ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
A61K 31/5415
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
54having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
5415ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
A61K 31/70
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
Applicants
  • THETA BIOMEDICAL CONSULTING & DEVELOPMENT CO., INC [US]/[US] (AllExceptUS)
  • THEOHARIDES, Theoharis, C. [US]/[US] (UsOnly)
Inventors
  • THEOHARIDES, Theoharis, C.
Agents
  • SUPERKO, Colleen
Priority Data
12/151,26806.05.2008US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD FOR PROTECTING HUMANS AGAINST SUPERFICIAL VASODILATOR FLUSH SYNDROME
(FR) PROCÉDÉ DE PROTECTION DES ÊTRES HUMAINS CONTRE LE SYNDROME DES BOUFFÉES DE VASODILATATION SUPERFICIELLE
Abstract
(EN)
Methods for protection of a human from superficial vasodilator flush syndrome comprise the administration of a flavonoid compound of the basic structures 2- phenyl-4H-1 -benzopyran or 2-phenyl-4-keto-1 -benzopyran or glycosides thereof, alone or, optionally, together with one or more of an olive kernel extract, a non- bovine sulfated proteoglycan, bitter willow extract, a D-hexosamine sulfate, S- adenosylmethione, folic acid, vitamin B12 and a serotonin inhibitor. Such treatment prevents, reduces or eliminates SVFS in patients.
(FR)
L'invention porte sur des procédés de protection d'un être humain contre le syndrome des bouffées de vasodilatation superficielle. Ces procédés comprennent l'administration d'un composé flavonoïde des structures de base 2-phényl-4H-1-benzopyrane ou 2-phényl-4-céto-1-benzopyrane ou glycosides de celles-ci, individuellement ou, facultativement, conjointement avec un ou plusieurs parmi un extrait de noyau d'olive, un protéoglycane sulfaté non bovin, un extrait de saule amer, un sulfate de D-hexosamine, la S-adénosylméthione, l'acide folique, la vitamine B12 et un inhibiteur de la sérotonine. Un tel traitement empêche, réduit ou élimine le syndrome des bouffées de vasodilatation superficielle chez les patients.
Also published as
Latest bibliographic data on file with the International Bureau