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1. (WO2009137510) METHOD FOR PROTECTING HUMANS AGAINST SUPERFICIAL VASODILATOR FLUSH SYNDROME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/137510    International Application No.:    PCT/US2009/042888
Publication Date: 12.11.2009 International Filing Date: 05.05.2009
IPC:
A61K 31/35 (2006.01), A61K 31/44 (2006.01), A61K 36/00 (2006.01)
Applicants: THETA BIOMEDICAL CONSULTING & DEVELOPMENT CO., INC [US/US]; 14 Parkman Street Brookline, MA 02446 (US) (For All Designated States Except US).
THEOHARIDES, Theoharis, C. [US/US]; (US) (For US Only)
Inventors: THEOHARIDES, Theoharis, C.; (US)
Agent: SUPERKO, Colleen; (US)
Priority Data:
12/151,268 06.05.2008 US
Title (EN) METHOD FOR PROTECTING HUMANS AGAINST SUPERFICIAL VASODILATOR FLUSH SYNDROME
(FR) PROCÉDÉ DE PROTECTION DES ÊTRES HUMAINS CONTRE LE SYNDROME DES BOUFFÉES DE VASODILATATION SUPERFICIELLE
Abstract: front page image
(EN)Methods for protection of a human from superficial vasodilator flush syndrome comprise the administration of a flavonoid compound of the basic structures 2- phenyl-4H-1 -benzopyran or 2-phenyl-4-keto-1 -benzopyran or glycosides thereof, alone or, optionally, together with one or more of an olive kernel extract, a non- bovine sulfated proteoglycan, bitter willow extract, a D-hexosamine sulfate, S- adenosylmethione, folic acid, vitamin B12 and a serotonin inhibitor. Such treatment prevents, reduces or eliminates SVFS in patients.
(FR)L'invention porte sur des procédés de protection d'un être humain contre le syndrome des bouffées de vasodilatation superficielle. Ces procédés comprennent l'administration d'un composé flavonoïde des structures de base 2-phényl-4H-1-benzopyrane ou 2-phényl-4-céto-1-benzopyrane ou glycosides de celles-ci, individuellement ou, facultativement, conjointement avec un ou plusieurs parmi un extrait de noyau d'olive, un protéoglycane sulfaté non bovin, un extrait de saule amer, un sulfate de D-hexosamine, la S-adénosylméthione, l'acide folique, la vitamine B12 et un inhibiteur de la sérotonine. Un tel traitement empêche, réduit ou élimine le syndrome des bouffées de vasodilatation superficielle chez les patients.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)