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Machine translation
1. (WO2009137465) COMPOSITIONS FOR TREATMENT OR PREVENTION OF PATHOLOGICAL CARDIAC REMODELING AND HEART FAILURE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/137465    International Application No.:    PCT/US2009/042823
Publication Date: 12.11.2009 International Filing Date: 05.05.2009
IPC:
A61K 31/404 (2006.01)
Applicants: UNIVERSITY OF ROCHESTER [US/US]; 601 Elmwood Ave., Box OTT Rochester, NY 14642 (US) (For All Designated States Except US).
YAN, Chen [CN/US]; (US) (For US Only).
LI, Jian-Dong [US/US]; (US) (For US Only)
Inventors: YAN, Chen; (US).
LI, Jian-Dong; (US)
Agent: MERKEL, Edwin, V.; Nixon Peabody LLP-Patent Group 1100 Clinton Square Rochester, NY 14604-1792 (US)
Priority Data:
61/050,308 05.05.2008 US
Title (EN) COMPOSITIONS FOR TREATMENT OR PREVENTION OF PATHOLOGICAL CARDIAC REMODELING AND HEART FAILURE
(FR) PROCÉDÉS ET COMPOSITIONS POUR LE TRAITEMENT OU LA PRÉVENTION D'UNE REMODÉLISATION CARDIAQUE PATHOLOGIQUE ET D'UNE INSUFFISANCE CARDIAQUE
Abstract: front page image
(EN)The invention relates to methods of treating or preventing pathological cardiac remodeling and/or preventing heart failure. These methods include the administration of a PDEl inhibitor to a patient under conditions effective to treat or prevent pathological cardiac remodeling, and therefore heart failure that occurs as a result of such remodeling. Pharmaceutical compositions and delivery vehicles that can be used in the methods of the present invention are also disclosed herein.
(FR)L'invention porte sur des procédés de traitement ou de prévention d'une remodélisation cardiaque pathologique et/ou de prévention d'une insuffisance cardiaque. Ces procédés comprennent l'administration d'un inhibiteur de PDEl à un patient dans des conditions efficaces pour traiter ou prévenir une remodélisation cardiaque pathologique, et en conséquence une insuffisance cardiaque qui se produit par suite d'une telle remodélisation. L'invention porte également sur des compositions pharmaceutiques et sur des véhicules d'administration qui peuvent être utilisés dans les procédés de la présente invention.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)