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Machine translation
1. (WO2009136249) AN IMPROVED PROCESS FOR THE PREPARATION OF LEVOTHYROXINE SODIUM WITH REDUCED LEVELS OF IMPURITIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/136249    International Application No.:    PCT/IB2009/005468
Publication Date: 12.11.2009 International Filing Date: 04.05.2009
IPC:
C07C 227/16 (2006.01), C07C 229/08 (2006.01)
Applicants: CADILA PHARMACEUTICALS LTD. [IN/IN]; "Cadila Corporate Campus" Sarkhej-Dholka Road Bhat Ahmedabad 382 210, Gujarat (IN) (For All Designated States Except US).
KHAMAR, Bakulesh Mafatlal [IN/IN]; (IN) (For US Only).
GURUSAMY, Renugadevi [IN/IN]; (IN) (For US Only).
RAVI, Maruti, Naik [IN/IN]; (IN) (For US Only).
REDDY, Vedururi, Madhava [IN/IN]; (IN) (For US Only).
EDDE, Balasubrahmanyam [IN/IN]; (IN) (For US Only).
PONNAIAH, Ravi [IN/IN]; (IN) (For US Only).
MODI, Indravadan, Ambalal [IN/IN]; (IN) (For US Only)
Inventors: KHAMAR, Bakulesh Mafatlal; (IN).
GURUSAMY, Renugadevi; (IN).
RAVI, Maruti, Naik; (IN).
REDDY, Vedururi, Madhava; (IN).
EDDE, Balasubrahmanyam; (IN).
PONNAIAH, Ravi; (IN).
MODI, Indravadan, Ambalal; (IN)
Common
Representative:
KHAMAR, Bakulesh Mafatlal [IN/IN]; (IN)
Priority Data:
991/MUM/2008 09.05.2008 IN
Title (EN) AN IMPROVED PROCESS FOR THE PREPARATION OF LEVOTHYROXINE SODIUM WITH REDUCED LEVELS OF IMPURITIES
(FR) PROCÉDÉ AMÉLIORÉ POUR LA PRÉPARATION DE LÉVOTHYROXINE SODIQUE PRÉSENTANT DES TAUX RÉDUITS D’IMPURETÉS
Abstract: front page image
(EN)The invention relates to an improved process for the preparation of Levothyroxine sodium with reduced levels of impurities. The invention also provides Levothyroxine sodium pentahydrate free from 3,5-Diiodothyronine or d-enantiomer of thyroxine. The invention also provides Levothyroxine sodium pentahydrate having liothyronine below 0.5% wt / wt.
(FR)L’invention concerne un procédé amélioré pour la préparation de lévothyroxine sodique présentant des taux réduits d’impuretés. L’invention concerne également une lévothyroxine sodique pentahydratée ne contenant pas de 3,5-diiodothyronine ou l’énantiomère d de la thyroxine. L’invention concerne en outre une lévothyroxine sodique pentahydratée contenant moins de 0,5 % en poids/poids de liothyronine.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)