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Machine translation
1. (WO2009135579) POLYMORPH OF 8-HYDROXY-5- [(1R)-1-HYDROXY-2- [[(1R) -2-(4-METHOXYPHENYL) -1-METHYLETHYL] AMINO] ETHYL] -2(1H)-QUINOLINONE MONOHYDROCHLORIDE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/135579    International Application No.:    PCT/EP2009/002549
Publication Date: 12.11.2009 International Filing Date: 07.04.2009
IPC:
C07D 215/26 (2006.01), A61K 31/4704 (2006.01), A61P 29/00 (2006.01), A61P 11/00 (2006.01)
Applicants: CHIESI FARMACEUTICI S.p.A. [IT/IT]; Via Palermo, 26/A I-43100 Parma (IT) (For All Designated States Except US).
PIVETTI, Fausto [IT/IT]; (IT) (For US Only).
LUTERO, Emilio [IT/IT]; (IT) (For US Only)
Inventors: PIVETTI, Fausto; (IT).
LUTERO, Emilio; (IT)
Agent: MINOJA, Fabrizio; BIANCHETTI BRACCO MINOJA S.r.l. Via Plinio, 63 I-20129 Milano (IT)
Priority Data:
08155799.3 07.05.2008 EP
Title (EN) POLYMORPH OF 8-HYDROXY-5- [(1R)-1-HYDROXY-2- [[(1R) -2-(4-METHOXYPHENYL) -1-METHYLETHYL] AMINO] ETHYL] -2(1H)-QUINOLINONE MONOHYDROCHLORIDE
(FR) POLYMORPHE DE 8-HYDROXY-5-[(1R)-1-HYDROXY-2-[[(1R)-2-(4-MÉTHOXYPHÉNYL)-1-MÉTHYLÉTHYL]- AMINO]ÉTHYL]-2(1H)-QUINOLINONE MONOHYDROCHLORHYDRATE
Abstract: front page image
(EN)The present invention relates to a novel polymorphic crystal form of 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]- amino]ethyl]-2(1H)-quinolinone monohydrochloride. The invention also relates to processes for its preparation, pharmaceutical compositions thereof, and to its use as a medicament.
(FR)L'invention concerne une nouvelle forme cristalline polymorphe de 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-méthoxyphényl)-1-méthyléthyl]- amino]éthyl]-2(1H)-quinolinone monohydrochlorhydrate. Elle concerne également des procédés de préparation de celle-ci, des compositions pharmaceutiques la contenant, ainsi que son utilisation en tant que médicament.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)