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1. (WO2009135056) RECOMBINANT DNA VECTORS FOR EXPRESSION OF HUMAN PROLACTIN ANTAGONISTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/135056    International Application No.:    PCT/US2009/042393
Publication Date: 05.11.2009 International Filing Date: 30.04.2009
IPC:
C07K 14/575 (2006.01), C12N 15/70 (2006.01)
Applicants: MONSANTO TECHNOLOGY LLC [US/US]; 800 North Lindbergh Boulevard St. Louis, MO 63167 (US) (For All Designated States Except US).
BOGOSIAN, Gregg [US/US]; (US) (For US Only).
MORRIS, Patricia [US/US]; (US) (For US Only).
CHOU, Jennifer [US/US]; (US) (For US Only).
ALLEN, Kimberly [US/US]; (US) (For US Only).
FRANTZ, Julia [US/US]; (US) (For US Only).
STORRS, Brad [US/US]; (US) (For US Only).
TOU, Jacob [US/US]; (US) (For US Only)
Inventors: BOGOSIAN, Gregg; (US).
MORRIS, Patricia; (US).
CHOU, Jennifer; (US).
ALLEN, Kimberly; (US).
FRANTZ, Julia; (US).
STORRS, Brad; (US).
TOU, Jacob; (US)
Agent: MCBRIDE, Timothy, B.; (US)
Priority Data:
61/049,122 30.04.2008 US
61/050,392 05.05.2008 US
61/090,634 21.08.2008 US
61/138,673 18.12.2008 US
Title (EN) RECOMBINANT DNA VECTORS FOR EXPRESSION OF HUMAN PROLACTIN ANTAGONISTS
(FR) VECTEURS D’ADN RECOMBINÉ DESTINÉS À L’EXPRESSION D’ANTAGONISTES DE LA PROLACTINE HUMAINE
Abstract: front page image
(EN)Embodiments of the present invention relate generally to methods and compositions for producing human prolactin antagonists. Embodiments of the present invention also relate to various methods for improved production of human prolactin antagonists by microorganisms. These microorganisms, including Escherichia coli, can be transformed to enable the expression of human prolactin antagonists at high levels using conventional and inexpensive fermentation conditions and inexpensive induction conditions, as described herein.
(FR)Les modes de réalisation de la présente invention concernent de façon générale des méthodes et des compositions permettant de produire des antagonistes de la prolactine humaine. Les modes de réalisation de la présente invention concernent également diverses méthodes permettant la production améliorée d’antagonistes de la prolactine humaine par des  microorganismes. Ces microorganismes, comprenant Escherichia coli, peuvent être transformés pour permettre l’expression d’antagonistes de la prolactine humaine à forts rendements en utilisant des conditions de fermentation classiques et peu coûteuses et des conditions d’induction peu coûteuses, comme cela est décrit ici.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)