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Machine translation
1. (WO2009134876) IRREVERSIBLE ELECTROPORATION TO CREATE TISSUE SCAFFOLDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/134876    International Application No.:    PCT/US2009/042100
Publication Date: 05.11.2009 International Filing Date: 29.04.2009
IPC:
A61L 27/36 (2006.01)
Applicants: VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. [US/US]; 2200 Kraft Drive Suite 1050 Blacksburg, VA 24060 (US) (For All Designated States Except US).
DAVALOS, Rafael, V. [US/US]; (US) (For US Only)
Inventors: DAVALOS, Rafael, V.; (US)
Agent: MAYBERRY, Michele; New River Valley IP Law PO Box 10944 Blacksburg, VA 24062 (US)
Priority Data:
61/125,840 29.04.2008 US
Title (EN) IRREVERSIBLE ELECTROPORATION TO CREATE TISSUE SCAFFOLDS
(FR) ÉLECTROPORATION IRRÉVERSIBLE DESTINÉE À CRÉER DES ÉCHAFAUDAGES TISSULAIRES
Abstract: front page image
(EN)The present invention provides engineered tissue scaffolds, engineered tissues, and methods of using them. The scaffolds and tissues are derived from natural tissues and are created using non-thermal irreversible electroporation (IRE). Use of IRE allows for ablation of cells of the tissue to be treated, but allows vascular and neural structures to remain essentially unharmed. Use of IRE thus permits preparation of thick tissue scaffolds and tissues due to the presence of vasculature within the scaffolds. The engineered tissues can be used in methods of treating subjects, such as those in need of tissue replacement or augmentation.
(FR)La présente invention concerne des échafaudages tissulaires modifiés, des tissus modifiés et des procédés d’utilisation de ceux-ci. Les échafaudages et les tissus sont dérivés de tissus naturels et sont créés au moyen de l’électroporation irréversible non-thermique (IRE). L’utilisation de l’IRE permet l’ablation de cellules du tissu devant être traité, tout en laissant les structures vasculaires et neurales essentiellement indemnes. L’utilisation de l’IRE permet ainsi la préparation de tissus et d’échafaudages tissulaires épais grâce à la présence d’un réseau vasculaire dans les échafaudages. Les tissus modifiés peuvent être utilisés dans des procédés de traitement de sujets, tels que ceux ayant besoin d’un remplacement ou d’une augmentation tissulaire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)