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1. (WO2009134870) POTENT CELL-BINDING AGENT DRUG CONJUGATES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/134870    International Application No.:    PCT/US2009/042091
Publication Date: 05.11.2009 International Filing Date: 29.04.2009
IPC:
A61K 31/00 (2006.01)
Applicants: IMMUNOGEN, INC. [US/US]; 830 Winter Street Waltham, MA 02451 (US) (For All Designated States Except US).
CHARI, Ravi, V., J. [US/US]; (US) (For US Only)
Inventors: CHARI, Ravi, V., J.; (US)
Agent: MACK, Susan, J.; (US)
Priority Data:
61/049,296 30.04.2008 US
Title (EN) POTENT CELL-BINDING AGENT DRUG CONJUGATES
(FR) CONJUGUÉS DE MÉDICAMENT D’AGENT DE LIAISON CELLULAIRE PUISSANT
Abstract: front page image
(EN)The present invention relates to the use of about 2 to about 8 drug molecules, for example, maytansinoid, per cell binding agent, such as an antibody, and maximal efficacy as compared to a drug load of lesser or higher number of drugs linked to such a cell binding agent.
(FR)La présente invention concerne l’utilisation d’environ 2 à environ 8 molécules de médicament, par exemple de maytansinoïde, par agent de liaison cellulaire, tel qu’un anticorps, avec une efficacité maximale comparée à une charge médicamenteuse d’un nombre inférieur ou supérieur de médicaments liés à un tel agent de liaison cellulaire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)