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Machine translation
1. (WO2009134725) MONOMETHYLAMINE PROGESTERON ANTAGONISTS SUCH AS CDB-4453 IN THE TREATMENT OF ENDOMETRIOSIS, UTERINE FIBROIDS, DYSMENORRHEA, BREAST CANCER ETC
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/134725    International Application No.:    PCT/US2009/041841
Publication Date: 05.11.2009 International Filing Date: 27.04.2009
IPC:
A61K 31/56 (2006.01), A61P 15/00 (2006.01), A61P 15/04 (2006.01), A61P 35/00 (2006.01)
Applicants: REPROS THERAPEUTICS INC. [US/US]; 2408 Timberloch Place, Suite B-7 The Woodlands, TX 77380 (US) (For All Designated States Except US).
PODOLSKI, Joseph, S. [US/US]; (US) (For US Only).
WIEHLE, Ronald, D. [US/US]; (US) (For US Only)
Inventors: PODOLSKI, Joseph, S.; (US).
WIEHLE, Ronald, D.; (US)
Agent: CLOUGH, David, W.; Howrey LLP Docketing Department 2941 Fairview Park Drive, Suite 200 Falls Church, VA 22042-2924 (US)
Priority Data:
61/048,459 28.04.2008 US
Title (EN) MONOMETHYLAMINE PROGESTERON ANTAGONISTS SUCH AS CDB-4453 IN THE TREATMENT OF ENDOMETRIOSIS, UTERINE FIBROIDS, DYSMENORRHEA, BREAST CANCER ETC
(FR) COMPOSITIONS ET PROCÉDÉS POUR TRAITER DES ÉTATS DÉPENDANTS DE LA PROGESTÉRONE
Abstract: front page image
(EN)The subject matter of the instant invention is pertinent to the field of treatment of progesterone-dependent conditions. Compositions for practicing the methods, comprising one or more 19-norsteroid progesterone receptor modulators having a monomethylamine-substituted phenyl ring at the 11 β-position of carbon 11 and exhibiting low antiglucocorticoid activity, are also disclosed. Embodiments of the instant invention disclose methods for treating endometriosis, dysmenorrhea, breast cancer, uterine fibroids and endometrial hyperproliferation.
(FR)La présente invention concerne le domaine du traitement d'états dépendant de la progestérone. L'invention porte sur des compositions pour la mise en œuvre des procédés, comportant un ou plusieurs modulateurs du récepteur de la progestérone 19-norstéroïde ayant un noyau phényle substitué par monoéthylamine en position β du carbone 11 et présentant une faible activité antiglucocorticoïde. Des modes de réalisation de la présente invention portent sur des procédés pour traiter l'endométriose, la dysménorrhée, le cancer du sein, les fibromes utérins et l’hyper prolifération endométriale.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)