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1. (WO2009134487) OPTIMIZED METHODS FOR DELIVERY OF DSRNA TARGETING THE PCSK9 GENE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/134487    International Application No.:    PCT/US2009/032743
Publication Date: 05.11.2009 International Filing Date: 30.01.2009
IPC:
C07H 21/04 (2006.01)
Applicants: ALNYLAM PHARMACEUTICALS, INC. [US/US]; 300 Third Street Third Floor Cambridge, MA 02142 (US) (For All Designated States Except US).
FITZGERALD, Kevin [US/US]; (US) (For US Only).
DE FOUGEROLLES, Antonin [CA/US]; (US) (For US Only).
AKINC, Akin [US/US]; (US) (For US Only).
KOTELIANSKI, Victor, E. [US/US]; (US) (For US Only)
Inventors: FITZGERALD, Kevin; (US).
DE FOUGEROLLES, Antonin; (US).
AKINC, Akin; (US).
KOTELIANSKI, Victor, E.; (US)
Agent: SHUSTER, Michael, J.; (US)
Priority Data:
61/024,968 31.01.2008 US
61/039,083 24.03.2008 US
61/076,548 27.06.2008 US
61/188,765 11.08.2008 US
Title (EN) OPTIMIZED METHODS FOR DELIVERY OF DSRNA TARGETING THE PCSK9 GENE
(FR) PROCÉDÉS OPTIMISÉS D'ADMINISTRATION D'ARNDS CIBLANT LE GÈNE PCSK9
Abstract: front page image
(EN)This invention relates to optimized methods for treating diseases caused by PCSK9 gene expression.
(FR)La présente invention concerne des procédés optimisés de traitement de maladies provoquées par l'expression du gène PCSK9.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)