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1. (WO2009134276) FERMENTIVE PRODUCTION OF FOUR CARBON ALCOHOLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/134276    International Application No.:    PCT/US2008/063852
Publication Date: 05.11.2009 International Filing Date: 16.05.2008
IPC:
C12N 1/00 (2006.01), C12N 1/21 (2006.01), C12N 1/32 (2006.01), C12P 7/16 (2006.01)
Applicants: BUTAMAX™ ADVANCED BIOFUELS LLC [US/US]; 200 Powder Mill Road Wilmington, DE 19803 (US) (For All Designated States Except US).
DONALDSON, Gail, K. [US/US]; (US) (For US Only).
ELIOT, Andrew, C. [US/US]; (US) (For US Only).
MAGGIO-HALL, Lori, Ann [US/US]; (US) (For US Only).
NAGARAJAN, Vasantha [US/US]; (US) (For US Only).
NAKAMURA, Charles, E. [US/US]; (US) (For US Only).
TOMB, Jean-Francois [US/US]; (US) (For US Only)
Inventors: DONALDSON, Gail, K.; (US).
ELIOT, Andrew, C.; (US).
MAGGIO-HALL, Lori, Ann; (US).
NAGARAJAN, Vasantha; (US).
NAKAMURA, Charles, E.; (US).
TOMB, Jean-Francois; (US)
Agent: FELTHAM, S., Neil; E. I. du Pont de Nemours and Company, Legal Patent Records Center, 4417 Lancaster Pike, Wilmington, Delaware 19805 (US)
Priority Data:
12/111,359 29.04.2008 US
Title (EN) FERMENTIVE PRODUCTION OF FOUR CARBON ALCOHOLS
(FR) PRODUCTION PAR FERMENTATION DE QUATRE ALCOOLS CARBONÉS
Abstract: front page image
(EN)Methods for the fermentive production of four carbon alcohols are provided. Specifically, butanol, preferably 2-butanol is produced by the fermentive growth of a recombinant bacteria expressing a 2- butanol biosynthetic pathway. The recombinant microorganisms and methods of the invention can also be adapted to produce 2-butanone, an intermediate in the 2-butanol biosynthetic pathways disclosed herein. Specifically disclosed herein are the use of coenzyme B12-independent butanediol dehydratases that catalyzes the substrate to product conversion of 2,3-butanediol to 2-butanone in the process of producing 2-butanol and 2-butanone.
(FR)L'invention concerne des procédés de production par fermentation de quatre alcools carbonés. Spécifiquement, du butanol, de préférence du 2-butanol, est produit par la croissance fermentative d'une bactérie recombinée exprimant une voie de biosynthèse de 2-butanol. Les micro-organismes recombinés et les procédés de l'invention peuvent également être adaptés à la production de 2-butanone, un intermédiaire dans la voie de biosynthèse du 2-butanol décrite ici. Spécifiquement, l'invention concerne l'utilisation de la coenzyme butanediol déshydratase indépendante de B12 qui catalyse la conversion du substrat en produit de 2,3-butanediol en 2-butanone dans le processus de production de 2-butanol et de 2-butanone.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)