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1. (WO2009134147) LIPID COMPOSITIONS CONTAINING DERIVATIVES OF EPA AND DHA AN THEIR USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/134147    International Application No.:    PCT/NO2009/000170
Publication Date: 05.11.2009 International Filing Date: 30.04.2009
IPC:
C07C 33/02 (2006.01), A61K 31/10 (2006.01), A61K 31/232 (2006.01), A61K 31/661 (2006.01), A61P 3/06 (2006.01), A61P 3/10 (2006.01), A61P 9/00 (2006.01), C07C 305/14 (2006.01), C07C 69/24 (2006.01), C07F 9/113 (2006.01)
Applicants: PRONOVA BIOPHARMA NORGE AS [NO/NO]; Vollsveien 6 N-1366 Lysaker (NO) (For All Designated States Except US).
HOLMEIDE, Anne Kristin [NO/NO]; (NO) (For US Only).
ROSMAN, Jenny [SE/SE]; (SE) (For US Only).
HOVLAND, Ragnar [NO/NO]; (NO) (For US Only)
Inventors: HOLMEIDE, Anne Kristin; (NO).
ROSMAN, Jenny; (SE).
HOVLAND, Ragnar; (NO)
Agent: ZACCO NORWAY AS; P.O. Box 2003, Vika N-0125 Oslo (NO)
Priority Data:
61/049,982 02.05.2008 US
Title (EN) LIPID COMPOSITIONS CONTAINING DERIVATIVES OF EPA AND DHA AN THEIR USE THEREOF
(FR) COMPOSITIONS LIPIDIQUES RENFERMANT DES DÉRIVÉS D’EPA ET DE DHA ET LEUR UTILISATION
Abstract: front page image
(EN)The present invention relates to a lipid composition comprising at least pro-drugs of omega-3 polyunsaturated alcohols, which pro-drugs of omega-3 polyunsaturated alcohols comprise at least one pro-drug of (all-Z) 5,8,11,14,17-eicosapentaen-1-ol, and at least one pro-drug of (all-Z)-4,7,10,13,16,19-docosahexaen-1-ol and their use as a pharmaceutical, in particular for the treatment of elevated triglyceride levels. The invention also relates to methods for the preparation of these pro-drugs from marine oils.
(FR)La présente invention concerne une composition lipidique renfermant au moins des précurseurs d’alcools oméga-3 polyinsaturés, lesquels précurseurs d’alcools oméga-3 polyinsaturés comprennent au moins un précurseur du (tout Z)-5,8,11,14,17-éicosapentaén-1-ol et au moins un précurseur du (tout Z)-4,7,10,13,16,19-docosahexaén-1-ol et leur utilisation en tant que produit pharmaceutique, en particulier pour le traitement de taux élevés de triglycérides. L’invention a également pour objet des procédés de préparation de ces précurseurs à partir d’huiles marines.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)