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1. (WO2009134130) TREATMENT OF BLEEDING WITH LOW HALF-LIFE FIBRINOGEN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/134130    International Application No.:    PCT/NL2009/050234
Publication Date: 05.11.2009 International Filing Date: 29.04.2009
IPC:
A61K 38/36 (2006.01), A61P 7/04 (2006.01)
Applicants: PHARMING INTELLECTUAL PROPERTY BV [NL/NL]; Darwinweg 24 NL-2333 CR Leiden (NL) (For All Designated States Except US).
PIEPER, Frank [NL/NL]; (NL) (For US Only).
RELAN, Anurag [US/US]; (US) (For US Only).
FORSBERG, Erik, Jordahl [US/US]; (US) (For US Only)
Inventors: PIEPER, Frank; (NL).
RELAN, Anurag; (US).
FORSBERG, Erik, Jordahl; (US)
Agent: KETELAARS, Maarten; (NL)
Priority Data:
61/050,174 02.05.2008 US
Title (EN) TREATMENT OF BLEEDING WITH LOW HALF-LIFE FIBRINOGEN
(FR) TRAITEMENT DE SAIGNEMENT PAR UN FIBRINOGÈNE DE FAIBLE DEMI-VIE
Abstract: front page image
(EN)The invention provides low-half life fibrinogen as a result of recombinant expression or enzymatic and chemical removal. The low-half life fibrinogen is useful in treating or effecting prophylaxis of bleeding particularly in situations of an acute nature in which a high initial dose and rapid decline to normal or below normal levels is desirable.
(FR)L'invention porte sur un fibrinogène de faible demi-vie résultant de l'expression recombinante ou d'une élimination enzymatique et chimique. Le fibrinogène de faible demi-vie est utile dans le traitement ou la prophylaxie efficace d'un saignement, en particulier dans des situations critiques dans lesquelles une dose initiale élevée et une diminution rapide vers des taux normaux ou inférieurs à la normale sont désirables.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)