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1. (WO2009134120) MASS SPECTROMETRIC ANALYSIS OF SMALL MOLECULE ANALYTES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/134120    International Application No.:    PCT/NL2008/050267
Publication Date: 05.11.2009 International Filing Date: 29.04.2008
IPC:
G01N 33/68 (2006.01), G01N 33/94 (2006.01)
Applicants: ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM [NL/NL]; Dr. Molewaterplein 50, NL-3015 GE Rotterdam (NL) (For All Designated States Except US).
LUIDER, Theo Marten [NL/NL]; (NL) (For US Only).
VAN KAMPEN, Jeroen J.A. [NL/NL]; (NL) (For US Only)
Inventors: LUIDER, Theo Marten; (NL).
VAN KAMPEN, Jeroen J.A.; (NL)
Agent: HATZMANN, M.J.; Vereenigde, Johan de Wittlaan 7, NL-2517 JR Den Haag (NL)
Priority Data:
Title (EN) MASS SPECTROMETRIC ANALYSIS OF SMALL MOLECULE ANALYTES
(FR) ANALYSE PAR SPECTROMÉTRIE DE MASSE D’ANALYTES À PETITE MOLÉCULE
Abstract: front page image
(EN)The present invention relates to a method for analyzing a biological sample for the presence of a small molecule analyte comprising loading said sample on a MALDI mass spectrometric sample matrix and subjecting said sample to MALDI mass spectrometric analysis, characterized in that the MALDI matrix comprises 7-hydroxy-4-(trifluoromethyl)coumarin (HFMC) as a MALDI matrix compound.
(FR)La présente invention concerne un procédé pour analyser un échantillon biologique pour déterminer la présence d’un analyte à petite molécule comprenant le chargement dudit échantillon sur une matrice d’échantillon pour spectrométrie de masse MALDI et la soumission dudit échantillon à une analyse par spectrométrie de masse MALDI, caractérisé en ce que la matrice MALDI comprend de la 7-hydroxy-4-(trifluorométhyl)coumarine (HFMC) en tant que composé de matrice MALDI.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)