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1. (WO2009132921) SPIRO-INDOLE DERIVATIVES FOR THE TREATMENT OF PARASITIC DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/132921    International Application No.:    PCT/EP2009/053902
Publication Date: 05.11.2009 International Filing Date: 01.04.2009
IPC:
C07D 471/20 (2006.01), C07D 487/20 (2006.01), A61K 31/437 (2006.01), A61K 31/55 (2006.01), A61K 31/407 (2006.01), A61P 33/02 (2006.01), A61P 33/06 (2006.01), A61K 31/424 (2006.01), A61K 31/438 (2006.01), C07D 498/22 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Lichtstrasse 35 CH-4056 Basel (CH) (For All Designated States Except US).
ANG, Shi Hua [SG/SG]; (SG) (For US Only).
KRASTEL, Philipp [DE/CH]; (CH) (For US Only).
LEONG, Seh Yong [SG/SG]; (SG) (For US Only).
TAN, Liying Jocelyn [SG/SG]; (SG) (For US Only).
WONG, Wei Lin Josephine [SG/SG]; (SG) (For US Only).
YEUNG, Bryan KS [US/SG]; (SG) (For US Only).
ZOU, Bin [CN/SG]; (SG) (For US Only)
Inventors: ANG, Shi Hua; (SG).
KRASTEL, Philipp; (CH).
LEONG, Seh Yong; (SG).
TAN, Liying Jocelyn; (SG).
WONG, Wei Lin Josephine; (SG).
YEUNG, Bryan KS; (SG).
ZOU, Bin; (SG)
Agent: ROSS, Richard A. M.; (CH)
Priority Data:
08155342.2 29.04.2008 EP
09151117.0 22.01.2009 EP
Title (EN) SPIRO-INDOLE DERIVATIVES FOR THE TREATMENT OF PARASITIC DISEASES
(FR) DÉRIVÉS SPIRO-INDOLES POUR LE TRAITEMENT DE MALADIES PARASITAIRES
Abstract: front page image
(EN)The invention relates to organic compounds which have interesting pharmaceutical properties. In particular, the compounds are useful in the treatment and/or prevention of infections such as those caused by Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, Trypanosoma cruzi and parasites of the Leishmania genus such as, for example, Leishmania donovani. The invention also relates to pharmaceutical compositions containing the compounds, as well as processes for their preparation.
(FR)L’invention concerne des composés organiques qui présentent des propriétés pharmaceutiques intéressantes. En particulier, les composés sont utiles dans le traitement et/ou la prévention d’infections telles que celles causées par Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, Trypanosoma cruzi et des parasites du genre Leishmania tels que, par exemple, Leishmania donovani. L’invention concerne également des compositions pharmaceutiques contenant les composés, ainsi que des procédés pour leur préparation.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)