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1. (WO2009132149) TREATMENT OF CONDITIONS RELATED TO CECAL LIGATION SHOCK

Pub. No.:    WO/2009/132149    International Application No.:    PCT/US2009/041464
Publication Date: Oct 29, 2009 International Filing Date: Apr 22, 2009
IPC: A61K 38/55
A61K 31/495
A61P 25/00
A61P 1/00
A61K 38/38
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
DELANO, Frank, A.
SCHMID-SCHONBEIN, Geert, W.
Inventors: DELANO, Frank, A.
SCHMID-SCHONBEIN, Geert, W.
Title: TREATMENT OF CONDITIONS RELATED TO CECAL LIGATION SHOCK
Abstract:
Techniques, methods and lavages are disclosed for prevention or treatment of shock, particularly cecal ligation or cecal inoculation shock, by administering a specific therapeutic agent, which is able to use smaller volumes of reagent to achieve partial to complete inhibition, than other previously described techniques. The agent includes a combination of enzyme inhibitor, cytotoxic lipid binding protein, and antibiotic.