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1. (WO2009131956) COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING TRIAZOLE DERIVATIVES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2009/131956 International Application No.: PCT/US2009/041162
Publication Date: 29.10.2009 International Filing Date: 20.04.2009
IPC:
A01N 43/64 (2006.01)
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
N
PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
43
Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
64
having rings with three nitrogen atoms as the only ring hetero atoms
Applicants:
RUSSELL, Michael, Geoffrey Neil [GB/GB]; GB (UsOnly)
DOYLE, Kevin, James [GB/GB]; GB (UsOnly)
INSTITUTE FOR ONEWORLD HEALTH [US/US]; 50 California Street, Suite 500 San Francisco, CA 94111, US (AllExceptUS)
Inventors:
RUSSELL, Michael, Geoffrey Neil; GB
DOYLE, Kevin, James; GB
Agent:
KONSKI, Antoinette, F.; US
Priority Data:
61/046,78021.04.2008US
Title (EN) COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING TRIAZOLE DERIVATIVES
(FR) COMPOSÉS, COMPOSITIONS ET PROCÉDÉS COMPRENANT DES DÉRIVÉS DE TRIAZOLE
Abstract:
(EN) The present invention relates to compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in need thereof an effective amount of a compound defined herein (including those compounds set forth in Tables 1-2 or encompassed by formulas I-II) or compositions thereof, thereby treating the disease. The present invention particularly, relates to a method of treating diarrhea and polycystic kidney disease.
(FR) La présente invention concerne des compositions et des procédés pour traiter une maladie chez un animal, cette maladie répondant à l'inhibition du polypeptide régulateur de la conductance transmembranaire de la mucoviscidose (CFTR), par administration à un mammifère le nécessitant d'une quantité efficace d'un composé défini ici (notamment les composés présentés dans les tableaux 1-2 ou représentés par les formules I-II) ou des compositions de ceux-ci, ce qui permet de traiter ainsi la maladie. La présente invention concerne en particulier un procédé de traitement de la diarrhée et de la polykystose rénale.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)