Processing

Please wait...

Settings

Settings

Goto Application

1. WO2009131954 - COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES

Publication Number WO/2009/131954
Publication Date 29.10.2009
International Application No. PCT/US2009/041159
International Filing Date 20.04.2009
IPC
A01N 43/82 2006.1
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
43Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
72having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms
82five-membered rings with three hetero atoms
A61K 31/41 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
CPC
A61P 13/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
12of the kidneys
C07D 271/06
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
271Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
02not condensed with other rings
061,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
Applicants
  • INSTITUTE FOR ONEWORLD HEALTH [US]/[US] (AllExceptUS)
  • JONES, Graham, Peter [GB]/[GB] (UsOnly)
  • DOYLE, Kevin, James [GB]/[GB] (UsOnly)
Inventors
  • JONES, Graham, Peter
  • DOYLE, Kevin, James
Agents
  • KONSKI, Antoinette, F.
Priority Data
61/046,76121.04.2008US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING OXADIAZOLE DERIVATIVES
(FR) COMPOSÉS, COMPOSITIONS ET PROCÉDÉS COMPRENANT DES DÉRIVÉS OXADIAZOLE
Abstract
(EN) The present invention relates to compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in need thereof an effective amount of a compound defined herein (including those compounds set forth in Table 1 or encompassed by formula I, II, or III) or compositions thereof, thereby treating the disease. The present invention particularly, relates to a method of treating diarrhea and polycystic kidney disease.
(FR) L'invention concerne des compositions et des procédés destinés à traiter une maladie chez un animal, ladite maladie réagissant à l'inhibition d'un polypeptide fonctionnel régulateur de la perméabilité transmembranaire de la fibrose cystique (CFTR). Ces procédés consistent à administrer, à un mammifère nécessitant un tel traitement, une quantité efficace d'un composé défini dans la description (y compris les composés définis dans le tableau 1 ou inclus dans les formules I,II ou III) ou de compositions de celui-ci, pour traiter ladite maladie. L'invention concerne en particulier un procédé de traitement de la diarrhée et d'une maladie polykystique des reins.
Related patent documents
Latest bibliographic data on file with the International Bureau