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1. (WO2009131837) SYSTEMS, METHODS AND COMPOSITIONS FOR OPTICAL STIMULATION OF TARGET CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/131837    International Application No.:    PCT/US2009/039949
Publication Date: 29.10.2009 International Filing Date: 08.04.2009
IPC:
C12N 13/00 (2006.01)
Applicants: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY. [US/US]; 1705 El Camino Real Palo Alto, CA 94306-1106 (US) (For All Designated States Except US).
ZHANG, Feng [US/US]; (US) (For US Only).
DEISSEROTH, Karl [US/US]; (US) (For US Only).
GRADINARU, Viviana [RO/US]; (US) (For US Only)
Inventors: ZHANG, Feng; (US).
DEISSEROTH, Karl; (US).
GRADINARU, Viviana; (US)
Agent: CRAWFORD, Robert, J.; (US)
Priority Data:
61/047,219 23.04.2008 US
Title (EN) SYSTEMS, METHODS AND COMPOSITIONS FOR OPTICAL STIMULATION OF TARGET CELLS
(FR) SYSTÈMES, PROCÉDÉS ET COMPOSITIONS PERMETTANT LA STIMULATION OPTIQUE DE CELLULES CIBLES
Abstract: front page image
(EN)Methods, systems and devices are implemented in connection with light- responsive ion channel molecules. One such method is implemented using a light- activated ion channel molecule that responds to a light stimulus. The method includes engineering the light-activated ion channel molecule in a cell; and activating the ion channel molecule, in response to light stimulus that is provided to the ion channel molecule and that has properties that do not activate a ChR2 ion channel, to allow ions to pass through the light-activated ion channel molecule.
(FR)L’invention concerne des procédés, systèmes et dispositifs mis en œuvre en relation avec les molécules des canaux ioniques sensibles à la lumière. Un tel procédé est mis en œuvre à l’aide d’une molécule de canal ionique activée par la lumière répondant à un stimulus lumineux. Le procédé comprend la génération de la molécule de canal ionique activée par la lumière dans une cellule; et l’activation de ladite molécule de canal ionique en réaction au stimulus lumineux appliqué à ladite molécule de canal ionique et possédant des propriétés n’activant pas le canal ionique ChR2, pour permettre aux ions de passer à travers ladite molécule de canal ionique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)