WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2009130602) FACTOR IX CONJUGATES WITH EXTENDED HALF-LIVES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/130602    International Application No.:    PCT/IB2009/005763
Publication Date: 29.10.2009 International Filing Date: 24.04.2009
IPC:
A61K 47/48 (2006.01), C12N 9/64 (2006.01), A61P 7/04 (2006.01)
Applicants: CELTIC PHARMA PEG LTD.; Cumberland House 1 Victoria Street Hamilton HM 11 (BM) (For All Designated States Except US).
HENRY, William [GB/GB]; (GB) (For US Only)
Inventors: HENRY, William; (GB)
Agent: WEBER, Martin et al.; Jones Day Prinzregentenstr. 11 80538 München (DE)
Priority Data:
61/047,544 24.04.2008 US
Title (EN) FACTOR IX CONJUGATES WITH EXTENDED HALF-LIVES
(FR) CONJUGUÉS DE FACTEUR IX DOTÉS DE DEMI-VIES PROLONGÉES
Abstract: front page image
(EN)The present invention relates to conjugates of Factor IX that have been modified to include a biocompatible polymer moiety. The Factor IX conjugates are substantially free of contamination by Factor IXa. The Factor IX conjugates have improved pharmacokinetic properties, such as increased half-life, which results in dose sparing and less frequent administration.
(FR)La présente invention concerne des conjugués de facteur IX qui ont été modifiés pour inclure une partie de polymère biocompatible. Les conjugués de facteur IX sont sensiblement exempts de contamination par le facteur IXa. Les conjugués de facteur IX présentent des propriétés pharmacocinétiques améliorées, comme une demi-vie accrue, qui permettent de limiter les doses et de réduire la fréquence d'administration.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)