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1. (WO2009129538) HUMAN EQUIVALENT MONOCLONAL ANTIBODIES ENGINEERED FROM NONHUMAN VARIABLE REGIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2009/129538    International Application No.:    PCT/US2009/041144
Publication Date: 22.10.2009 International Filing Date: 20.04.2009
IPC:
C07K 16/00 (2006.01), C07K 16/28 (2006.01), C07K 16/22 (2006.01)
Applicants: XENCOR, INC. [US/US]; 111 W. Lemon Avenue Monrovia, CA 91016 (US) (For All Designated States Except US).
BERNETT, Matthew, J. [US/US]; (US) (For US Only).
MOORE, Gregory [US/US]; (US) (For US Only).
DESJARLAIS, John, R. [US/US]; (US) (For US Only)
Inventors: BERNETT, Matthew, J.; (US).
MOORE, Gregory; (US).
DESJARLAIS, John, R.; (US)
Agent: SILVA, Robin, M.; (US)
Priority Data:
61/115,449 17.11.2008 US
61/120,675 08.12.2008 US
61/046,399 18.04.2008 US
Title (EN) HUMAN EQUIVALENT MONOCLONAL ANTIBODIES ENGINEERED FROM NONHUMAN VARIABLE REGIONS
(FR) ANTICORPS MONOCLONAUX D’ÉQUIVALENT HUMAIN CONÇUS À PARTIR DE RÉGIONS VARIABLES NON HUMAINES
Abstract: front page image
(EN)The present invention is directed to the creation of human equivalent CDRs and antibodies containing them by a method of producing an antibody which specifically binds to an antigen.
(FR)La présente invention concerne la création de CDR équivalents humains et d’anticorps les contenant par un procédé de production d’un anticorps qui se lie spécifiquement à un antigène.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)